Characteristics of the recombinant 4C(-) virus used in this study.

<p>(A) Sequences around the initiation codons (underlined) of the P, C’, C, Y1 and Y2 of WT and 4C(-) are shown, and mutated codons to silence the C related proteins in the 4C(-) sequence are highlighted in bold. (B) Schematic representation of C protein of the 4C(-) recombinant. Amino acid changes for the 4C(-) mutant are indicated.