OxLDL-induced reduction in UCP2 protein was restored by Kv1.5 siRNA, but exaggerated by Kv1.5 overexpression.

<p>The UCP2 protein expression was detected by western blot in HPAECs transfected with Kv1.5-siRNA (A) and or infected with adnovirus containing <i>KCNA5</i> (B). Digital photographs showing UCP2 protein expression are on the top panel and bar graph showing quantitative analysis of the total protein are on the lower panel. The values are presented as means ± SEM of 6 independent experiments. ** <i>P</i><0.01 vs. corresponding control group; # <i>P</i><0.01 vs. oxLDL group.