Detailed expression profiles for all the identified differentially expressed proteins, according to its functional categories: (A) cell metabolism; (B) unknown function; (C) Cell redox homeostasis; (D) protein folding and degradation; (E) translation.

<p>Grey bars represent fold change in protein expression in BTTR-wt versus the control while black bars represent fold change in protein expression in BTTR-L55P versus the control. The vertical axis indicates the identified protein while the horizontal axis represents the fold variation in protein expression. Additional information for each protein, including full name, can be found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050123#pone-0050123-t001" target="_blank">Table 1</a>. For proteins identified in different spots (with slightly different fold variations) the average is represented in the graph.