Myeloma increased Gr-1+CD11b+cells in mice. A–B,

<p>Flow cytometry analysis showing the percentage of the Gr-1+CD11b+cells in bone marrow (A) and spleen (B) of control and 5TGM1-GFP inoculated mice 28 days after tumor inoculation. <b>C–D,</b> The quantification of flow cytometry of A–B. *P<0.05, n = 6. <b>C∼D,</b> Myeloma model validation. Percentage of 5TGM1-GFP+myeloma cells (<b>C</b>) and serum IgG2bκ level (mg/ml) (<b>B</b>) in C57BL6/KaLwRij mice increased with time after 5TGM1 myeloma cell inoculation. n = 6 for tumor group; n = 4 for control group.