Effect of acute ethanol exposure on myocardial gene expression.
- Shiliang Li (298790)
- Sevil Korkmaz (298791)
- Sivakkanan Loganathan (298792)
- Alexander Weymann (298793)
- Tamás Radovits (298794)
- Enikő Barnucz (298795)
- Kristóf Hirschberg (298796)
- Peter Hegedüs (298797)
- Yan Zhou (6523)
- Liang Tao (248968)
- Szabolcs Páli (298798)
- Gábor Veres (298799)
- Matthias Karck (298801)
- Gábor Szabó (75715)
Publication date
February 2013
DOIAbstract
<p>Quantitative real-time PCR from myocardium RNA extracts revealed that mRNA levels for (A) superoxide dismutase (SOD)-1, (B) glutathione peroxydase (GPx)-4, (C) cytochrome-c oxidase were significantly increased after 24 h and (D) matrix metalloproteinase (MMP)-9 following 6 h and 24 h compared with the control group. However, mRNA-levels of (E) L-Type calcium-channel (Ca<sub>v</sub>1.2), (F) sarco(endo)plasmic Ca<sup>2+</sup>-ATPase (SERCA)-2 and (G) sodium-potassium Adenosine Triphosphatase (Na<sup>+</sup>/K<sup>+</sup>-ATPase) remained unchanged following ethanol administration compared to the control group. Eth indicates ethanol. *p<0.05 versus control,<sup>#</sup>p<0.05 versus ethanol 1 h, <sup>$</sup>p<0.05 versus ethanol 6 h.</p
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