Progenitors expressing Mash1, Dlx2 and Tbr2 define distinct dorso-ventral microdomains of the adult mouse SVZ.

<p>(<b>A,C,E</b>) Heat maps showing the densities (from higher (red) to lower (blue) values) of quantified progenitors in 100 µm sized squares positioned along the dorsal and lateral LV walls at 5 representative rostro-caudal coordinates (1.2 as rostral, 0.6, 0, −0.6 and −1.2 as caudal). Counts and statistical analysis of the dorso-ventral distribution of Tbr2+ cells (<b>B</b>)<b>,</b> Dlx2+ cells (<b>D</b>) and Mash1+ cells (<b>F</b>) at defined rostro-caudal coordinates of the LV (rostral = 1.2; middle = 0; caudal = −1.2). Statistical analysis (Bonferroni’s followed by posthoc test) below histograms at rostro-caudal axis 1.2, 0 and −1.2 significance of quantified progenitors in individual SVZ microdomains. D-L = dorso-lateral; V-L = ventro-lateral ns = no significance; *p<0.05; **p<0.01; ***p<0.001.