<p>Formula: Genotype ∼ Left Hippocampus + (1|Age).</p><p>Fixed effects:</p><p>A generalised mixed-effect model is run using normalised volumes of left hemisphere grey matter structures and gender as explanatory variables together with age as a random effect. Genotype is set as the response variable. The final model is derived following an iterative model selection procedure that involves comparing successive models using Akaike's Information Criterion (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048895#s2" target="_blank">Methods</a> for detailed description of model selection procedure).</p
<p>Figure shows significant diagnosis by genotype interaction involving both right and left hippocam...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
<p>Formula: Genotype ∼ Right Hippocampus + Right Amygdala + (1|Age) where “∼” means modelled against...
<p>Formula: </p><p></p><p></p><p>“∼” means modelled against, and “(1| factor)” means that a factor i...
<p>Models:</p><p>Left hemisphere: Genotype ∼ Left Hippocampus + (1|Age).</p><p>Right hemisphere: Gen...
<p>Formula: </p><p></p><p></p><p>“∼” means modelled against, and “(1| factor)” means that a factor i...
<p>Render (X = 28mm, Y = -14mm, at p<0.001 unc.) and parameter estimates (and 95% CI) for each genot...
Imaging genetics is an emerging field for the investigation of neuro-mechanisms linked to genetic va...
a<p>Genotypes were tested separately in models including age and sex as <i>a priori</i> predictors. ...
<p>Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effe...
<p>Figure shows box plot depicting significant diagnosis by genotype interaction involving both righ...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
<p>Figure shows significant diagnosis by genotype interaction involving both right and left hippocam...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
<p>Formula: Genotype ∼ Right Hippocampus + Right Amygdala + (1|Age) where “∼” means modelled against...
<p>Formula: </p><p></p><p></p><p>“∼” means modelled against, and “(1| factor)” means that a factor i...
<p>Models:</p><p>Left hemisphere: Genotype ∼ Left Hippocampus + (1|Age).</p><p>Right hemisphere: Gen...
<p>Formula: </p><p></p><p></p><p>“∼” means modelled against, and “(1| factor)” means that a factor i...
<p>Render (X = 28mm, Y = -14mm, at p<0.001 unc.) and parameter estimates (and 95% CI) for each genot...
Imaging genetics is an emerging field for the investigation of neuro-mechanisms linked to genetic va...
a<p>Genotypes were tested separately in models including age and sex as <i>a priori</i> predictors. ...
<p>Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effe...
<p>Figure shows box plot depicting significant diagnosis by genotype interaction involving both righ...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...
<p>Figure shows significant diagnosis by genotype interaction involving both right and left hippocam...
Structural brain changes that occur during development and ageing are related to mental health and g...
Structural brain changes that occur during development and ageing are related to mental health and g...