Insulin tolerance test (ITT): (A) insulin sensitivity test after intraperitoneal injection of insulin (1.00 U/kg body wt) was performed on lean and obese groups.

<p>Blood samples were collected from the tail at indicated time points and analyzed for glucose concentration; (B) the constant rate for blood glucose disappearance (Kitt), based on the linear regression of the neperian logarithm of glucose concentrations, obtained from indicated time points. Results are expressed as mean ± SEM from 5–7 animals in each group.