Comparison of CDR3 region of the TCR β family between dnTGFβRII and dnTGFβRII IL-6^−/− mice.

<p>The arrows indicate clonal expansion of specific Vβ. C57B6 mice were used as negative control. With this technique, if there is no detectable T cell expansion within a Vβ spectrum, a Gaussian distribution of CDR3 lengths is observed. In contrast, clonal expansions are observed as a perturbation of this Gaussian distribution.