<p><b>A:</b> The panels show the assessment of cell division by successive dilution of CFSE at days 6, 9, and 12 of co-culture in the CD154/IL-4 system in one representative experiment. <b>B:</b> The graph shows the mean (±SEM) percentage of cells in each cell division at day 12 from six independent experiments (samples 34, 41, 46, 68, 69 and 70). <b>C:</b> The graph shows the mean (±SEM) cell counts determined for each condition and time point in all six experiments.</p
Introduction: Dasatinib is a dual SRC/ABL tyrosine kinase inhibitor used to treat chronic myeloid le...
<p><b>A.</b> Purified splenic CARTg CD4<sup>+</sup> T cells were transduced with empty vector or Ras...
<p>(<b>A</b>) CFb cultured on 24 well plates were serum starved for 12 h and then ± 50 nM dasatinib ...
<p><b>A:</b> Analysis of the effect of dasatinib on actin polymerization following CXCL12 treatment ...
<p>NB4 cells were treated with different concentrations of dasatinib for the indicated times. (A) Th...
Chemokines and their ligands play a critical role in enabling chronic lymphocytic leukaemia (CLL) ce...
<p>HL60 cells were treated with dasatinib for the indicated times. Aliquots of the cultures were wit...
<p>(A) Dasatinib decreases the number of MSC and OB cells in culture. The hMSC-TERT and the MG-63 ce...
<p>Representative microscopy images (left panels) of Caco-2, Colo205, DKO-1, DLD-1, and Lim1215 sphe...
As antigenic stimulation of the B cell antigen receptor (BCR) is key to chronic lymphocytic leukaemi...
In chronic myeloid leukemia (CML) cell lines, brief exposure to pharmacologically relevant dasatinib...
BackgroundThe proliferation of clonal cytotoxic T-cells or natural killer cells has been observed af...
<p>(<b>A</b>) CFb were cultured on coverslips for 2 h. For dasatinib treatment, the drug (50 nM) was...
<p>c-Cbl RING finger mutant mice aged 8–9 months were dosed daily with 30 mg/kg (am) +50 mg/kg (pm) ...
Introduction: Dasatinib is a dual SRC/ABL tyrosine kinase inhibitor used to treat chronic myeloid le...
Introduction: Dasatinib is a dual SRC/ABL tyrosine kinase inhibitor used to treat chronic myeloid le...
<p><b>A.</b> Purified splenic CARTg CD4<sup>+</sup> T cells were transduced with empty vector or Ras...
<p>(<b>A</b>) CFb cultured on 24 well plates were serum starved for 12 h and then ± 50 nM dasatinib ...
<p><b>A:</b> Analysis of the effect of dasatinib on actin polymerization following CXCL12 treatment ...
<p>NB4 cells were treated with different concentrations of dasatinib for the indicated times. (A) Th...
Chemokines and their ligands play a critical role in enabling chronic lymphocytic leukaemia (CLL) ce...
<p>HL60 cells were treated with dasatinib for the indicated times. Aliquots of the cultures were wit...
<p>(A) Dasatinib decreases the number of MSC and OB cells in culture. The hMSC-TERT and the MG-63 ce...
<p>Representative microscopy images (left panels) of Caco-2, Colo205, DKO-1, DLD-1, and Lim1215 sphe...
As antigenic stimulation of the B cell antigen receptor (BCR) is key to chronic lymphocytic leukaemi...
In chronic myeloid leukemia (CML) cell lines, brief exposure to pharmacologically relevant dasatinib...
BackgroundThe proliferation of clonal cytotoxic T-cells or natural killer cells has been observed af...
<p>(<b>A</b>) CFb were cultured on coverslips for 2 h. For dasatinib treatment, the drug (50 nM) was...
<p>c-Cbl RING finger mutant mice aged 8–9 months were dosed daily with 30 mg/kg (am) +50 mg/kg (pm) ...
Introduction: Dasatinib is a dual SRC/ABL tyrosine kinase inhibitor used to treat chronic myeloid le...
Introduction: Dasatinib is a dual SRC/ABL tyrosine kinase inhibitor used to treat chronic myeloid le...
<p><b>A.</b> Purified splenic CARTg CD4<sup>+</sup> T cells were transduced with empty vector or Ras...
<p>(<b>A</b>) CFb cultured on 24 well plates were serum starved for 12 h and then ± 50 nM dasatinib ...