Frequency distribution of genetic factors influencing iron metabolism in patients with and without hepatic iron accumulation.

Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients

McCune, Catherine Anne
Ravine, D.
Carter, K.
Jackson, H. A.
Dutton, D.
Hedderich, J.
Krawczak, M.
Worwood, Mark

January 2006

Background and aims: Although most cases of hereditary haemochromatosis are associated with homozygo...

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Benyamin, B.
Esko, T.
Ried, J.S.
Radhakrishnan, A.
Vermeulen, S.
Traglia, M.
Gogele, M.
Anderson, D.
Broer, L.
Podmore, C.
Luan, J.
Kutalik, Z.
Sanna, S.
Meer, P. van der
Tanaka, T.
Wang, F
Westra, H.J.
Franke, L.
Mihailov, E.
Milani, L.
Haldin, J.
Winkelmann, J.
Meitinger, T.
Thiery, J.
Peters, A.
Waldenberger, M.
Rendon, A.
Jolley, J.
Sambrook, J.
Kiemeney, L.A.L.M.
Sweep, C.G.J.
Sala, C.F.
Schwienbacher, C.
Pichler, I.
Hui, J.
Demirkan, A.
Isaacs, A.
Amin, N.
Steri, M.
Waeber, G.
Verweij, N.
Powell, J.E.
Nyholt, D.R.
Heath, A.C.
Madden, P.A.F.
Visscher, P.M.
Wright, M.J.
Montgomery, G.W.
Martin, N.G.
Hernandez, D.
Bandinelli, S.
Harst, P. van der
Uda, M.
Vollenweider, P.
Scott, R.A.
Langenberg, C.
Wareham, N.J.
InterAct, C.
Duijn, C. van
Beilby, J.
Pramstaller, P.P.
Hicks, A.A.
Ouwehand, W.H.
Oexle, K.
Gieger, C.
Metspalu, A.
Camaschella, C.
Toniolo, D.
Swinkels, D.W.
Whitfield, J.B.

January 2014

Contains fulltext : 137523.pdf (publisher's version ) (Open Access)Variation in bo...

Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

McLaren, Christine E.
McLachlan, Stela
Garner, Chad P.
Vulpe, Chris D.
Gordeuk, Victor R.
Eckfeldt, John H.
Adams, Paul C.
Acton, Ronald T.
Murray, Joseph A.
Leiendecker-Foster, Catherine
Snively, Beverly M.
Barcellos, Lisa F.
Cook, James D.
McLaren, Gordon D.

June 2012

The existence of multiple inherited disorders of iron metabolism suggests genetic contributions to i...

Genetics of hereditary hemochromatosis: A clinical perspective

Gan, E.
Trinder, D.
Ayonrinde, Oyekoya
Olynyk, John

January 2009

Hereditary hemochromatosis due to homozygosity for the C282Y mutation in the HFE gene product is the...

Frequency of Hereditary Hemochromatosis (HFE) Gene Mutations in Egyptian Beta Thalassemia Patients and its Relation to Iron Overload

Azza Aboul Enein
Nermine A. El Dessouky
Khalda S. Mohamed
Shahira K. A. Botros
Mona F. Abd El Gawad
Mona Hamdy
Nehal Dyaa

June 2016

AIM: This study aimed to detect the most common HFE gene mutations (C282Y, H63D, and S56C) in Egypti...

Relationship between clinical and genetic variables considered in the study with hepatic iron accumulation in 216 patients with NAFLD (univariate analysis).

Luca Valenti (300533)
Raffaela Rametta (43738)
Paola Dongiovanni (300534)
Benedetta M. Motta (300535)
Elena Canavesi (300536)
Serena Pelusi (300537)
Edoardo A. Pulixi (300538)
Anna L. Fracanzani (300539)
Silvia Fargion (300540)

February 2013

<p>ALT: alanine aminotransferases; BMI: body mass index; CRP: C reactive protein; TS%: transferrin s...

Facteurs acquis et génétiques de modulation de la pénétrance de l'hémochromatose HFE [Acquired and genetic factors influencing the penetrance of HFE haemochromatosis]

Deugnier, Yves
Bourgain, Catherine
Mosser, Jean

May 2008

International audienceC282Y homozygosity is necessary (but insufficient in isolation) for the onset ...

Associations of genetically determined iron status across the phenome: a mendelian randomization study

Gill, Dipender
Benyamin, Beben
Moore, Luke S. P.
Monori, Grace
Zhou, Ang
Koskeridis, Fotios
Evangelou, Evangelos
Laffan, Mike
Walker, Ann P.
Tsilidis, Konstantinos K.
Dehghan, Abbas
Elliott, Paul
Hyppönen, Elina
Tzoulaki, Ioanna

June 2019

BACKGROUND: Iron is integral to many physiological processes, and variations in its levels, even wit...

A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis

Constantine, Clare C.
Anderson, Greg J.
Vulpe, Chris D.
McLaren, Christine E.
Bahlo, Melanie
Yeap, Heng Lin
Gertig, Dorota M.
Osborne, Nicholas J.
Bertalli, Nadine A.
Beckman, Kenneth B.
Chen, Victoria
Matak, Pavel
McKie, Andrew T.
Delatycki, Martin B.
Olynyk, John K.
English, Dallas R.
Southey, Melissa C.
Giles, Graham G.
Hopper, John L.
Allen, Katrina J.
Gurrin, Lyle C.

October 2009

There is emerging evidence that there are genetic modifiers of iron indices for HFE gene mutation ca...

Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y

Wallace, Df
Walker, Ap
Pietrangelo, Antonello
Clare, M
Bomford, Ab
Dixon, Jl
Powell, Lw
Subramaniam, Vn
Dooley, Js

January 2002

Background/Aims: HFE-related haemochromatosis is a common disorder of iron metabolism. Most affected...

HFE mutations, iron deficiency and overload in 10,500 blood donors

Jackson, H. A.
Carter, Kymberley
Darke, C.
Guttridge, M. G.
Ravine, D.
Hutton, R. D.
Napier, J. A.
Worwood, Mark

August 2001

People with genetic haemochromatosis (GH) accumulate iron from excessive dietary absorption. In popu...

Associations of genetically determined iron status across the phenome: A mendelian randomization study.

Dipender Gill
Beben Benyamin
Luke S P Moore
Grace Monori
Ang Zhou
Fotios Koskeridis
Evangelos Evangelou
Mike Laffan
Ann P Walker
Konstantinos K Tsilidis
Abbas Dehghan
Paul Elliott
Elina Hyppönen
Ioanna Tzoulaki

June 2019

BackgroundIron is integral to many physiological processes, and variations in its levels, even withi...

Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients

McCune, Catherine Anne
Ravine, D.
Carter, K.
Jackson, H. A.
Dutton, D.
Hedderich, J.
Krawczak, M.
Worwood, Mark

January 2006

Background and aims: Although most cases of hereditary haemochromatosis are associated with homozygo...

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Benyamin, B.
Esko, T.
Ried, J.S.
Radhakrishnan, A.
Vermeulen, S.
Traglia, M.
Gogele, M.
Anderson, D.
Broer, L.
Podmore, C.
Luan, J.
Kutalik, Z.
Sanna, S.
Meer, P. van der
Tanaka, T.
Wang, F
Westra, H.J.
Franke, L.
Mihailov, E.
Milani, L.
Haldin, J.
Winkelmann, J.
Meitinger, T.
Thiery, J.
Peters, A.
Waldenberger, M.
Rendon, A.
Jolley, J.
Sambrook, J.
Kiemeney, L.A.L.M.
Sweep, C.G.J.
Sala, C.F.
Schwienbacher, C.
Pichler, I.
Hui, J.
Demirkan, A.
Isaacs, A.
Amin, N.
Steri, M.
Waeber, G.
Verweij, N.
Powell, J.E.
Nyholt, D.R.
Heath, A.C.
Madden, P.A.F.
Visscher, P.M.
Wright, M.J.
Montgomery, G.W.
Martin, N.G.
Hernandez, D.
Bandinelli, S.
Harst, P. van der
Uda, M.
Vollenweider, P.
Scott, R.A.
Langenberg, C.
Wareham, N.J.
InterAct, C.
Duijn, C. van
Beilby, J.
Pramstaller, P.P.
Hicks, A.A.
Ouwehand, W.H.
Oexle, K.
Gieger, C.
Metspalu, A.
Camaschella, C.
Toniolo, D.
Swinkels, D.W.
Whitfield, J.B.

January 2014

Contains fulltext : 137523.pdf (publisher's version ) (Open Access)Variation in bo...

Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

McLaren, Christine E.
McLachlan, Stela
Garner, Chad P.
Vulpe, Chris D.
Gordeuk, Victor R.
Eckfeldt, John H.
Adams, Paul C.
Acton, Ronald T.
Murray, Joseph A.
Leiendecker-Foster, Catherine
Snively, Beverly M.
Barcellos, Lisa F.
Cook, James D.
McLaren, Gordon D.

June 2012

The existence of multiple inherited disorders of iron metabolism suggests genetic contributions to i...

Genetics of hereditary hemochromatosis: A clinical perspective

Gan, E.
Trinder, D.
Ayonrinde, Oyekoya
Olynyk, John

January 2009

Hereditary hemochromatosis due to homozygosity for the C282Y mutation in the HFE gene product is the...

Frequency of Hereditary Hemochromatosis (HFE) Gene Mutations in Egyptian Beta Thalassemia Patients and its Relation to Iron Overload

Azza Aboul Enein
Nermine A. El Dessouky
Khalda S. Mohamed
Shahira K. A. Botros
Mona F. Abd El Gawad
Mona Hamdy
Nehal Dyaa

June 2016

AIM: This study aimed to detect the most common HFE gene mutations (C282Y, H63D, and S56C) in Egypti...

Relationship between clinical and genetic variables considered in the study with hepatic iron accumulation in 216 patients with NAFLD (univariate analysis).

Luca Valenti (300533)
Raffaela Rametta (43738)
Paola Dongiovanni (300534)
Benedetta M. Motta (300535)
Elena Canavesi (300536)
Serena Pelusi (300537)
Edoardo A. Pulixi (300538)
Anna L. Fracanzani (300539)
Silvia Fargion (300540)

February 2013

<p>ALT: alanine aminotransferases; BMI: body mass index; CRP: C reactive protein; TS%: transferrin s...

Facteurs acquis et génétiques de modulation de la pénétrance de l'hémochromatose HFE [Acquired and genetic factors influencing the penetrance of HFE haemochromatosis]

Deugnier, Yves
Bourgain, Catherine
Mosser, Jean

May 2008

International audienceC282Y homozygosity is necessary (but insufficient in isolation) for the onset ...

Associations of genetically determined iron status across the phenome: a mendelian randomization study

Gill, Dipender
Benyamin, Beben
Moore, Luke S. P.
Monori, Grace
Zhou, Ang
Koskeridis, Fotios
Evangelou, Evangelos
Laffan, Mike
Walker, Ann P.
Tsilidis, Konstantinos K.
Dehghan, Abbas
Elliott, Paul
Hyppönen, Elina
Tzoulaki, Ioanna

June 2019

BACKGROUND: Iron is integral to many physiological processes, and variations in its levels, even wit...

A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis

Constantine, Clare C.
Anderson, Greg J.
Vulpe, Chris D.
McLaren, Christine E.
Bahlo, Melanie
Yeap, Heng Lin
Gertig, Dorota M.
Osborne, Nicholas J.
Bertalli, Nadine A.
Beckman, Kenneth B.
Chen, Victoria
Matak, Pavel
McKie, Andrew T.
Delatycki, Martin B.
Olynyk, John K.
English, Dallas R.
Southey, Melissa C.
Giles, Graham G.
Hopper, John L.
Allen, Katrina J.
Gurrin, Lyle C.

October 2009

There is emerging evidence that there are genetic modifiers of iron indices for HFE gene mutation ca...

Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y

Wallace, Df
Walker, Ap
Pietrangelo, Antonello
Clare, M
Bomford, Ab
Dixon, Jl
Powell, Lw
Subramaniam, Vn
Dooley, Js

January 2002

Background/Aims: HFE-related haemochromatosis is a common disorder of iron metabolism. Most affected...

HFE mutations, iron deficiency and overload in 10,500 blood donors

Jackson, H. A.
Carter, Kymberley
Darke, C.
Guttridge, M. G.
Ravine, D.
Hutton, R. D.
Napier, J. A.
Worwood, Mark

August 2001

People with genetic haemochromatosis (GH) accumulate iron from excessive dietary absorption. In popu...

Associations of genetically determined iron status across the phenome: A mendelian randomization study.

Dipender Gill
Beben Benyamin
Luke S P Moore
Grace Monori
Ang Zhou
Fotios Koskeridis
Evangelos Evangelou
Mike Laffan
Ann P Walker
Konstantinos K Tsilidis
Abbas Dehghan
Paul Elliott
Elina Hyppönen
Ioanna Tzoulaki

June 2019

BackgroundIron is integral to many physiological processes, and variations in its levels, even withi...

Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients

McCune, Catherine Anne
Ravine, D.
Carter, K.
Jackson, H. A.
Dutton, D.
Hedderich, J.
Krawczak, M.
Worwood, Mark

January 2006

Background and aims: Although most cases of hereditary haemochromatosis are associated with homozygo...

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Benyamin, B.
Esko, T.
Ried, J.S.
Radhakrishnan, A.
Vermeulen, S.
Traglia, M.
Gogele, M.
Anderson, D.
Broer, L.
Podmore, C.
Luan, J.
Kutalik, Z.
Sanna, S.
Meer, P. van der
Tanaka, T.
Wang, F
Westra, H.J.
Franke, L.
Mihailov, E.
Milani, L.
Haldin, J.
Winkelmann, J.
Meitinger, T.
Thiery, J.
Peters, A.
Waldenberger, M.
Rendon, A.
Jolley, J.
Sambrook, J.
Kiemeney, L.A.L.M.
Sweep, C.G.J.
Sala, C.F.
Schwienbacher, C.
Pichler, I.
Hui, J.
Demirkan, A.
Isaacs, A.
Amin, N.
Steri, M.
Waeber, G.
Verweij, N.
Powell, J.E.
Nyholt, D.R.
Heath, A.C.
Madden, P.A.F.
Visscher, P.M.
Wright, M.J.
Montgomery, G.W.
Martin, N.G.
Hernandez, D.
Bandinelli, S.
Harst, P. van der
Uda, M.
Vollenweider, P.
Scott, R.A.
Langenberg, C.
Wareham, N.J.
InterAct, C.
Duijn, C. van
Beilby, J.
Pramstaller, P.P.
Hicks, A.A.
Ouwehand, W.H.
Oexle, K.
Gieger, C.
Metspalu, A.
Camaschella, C.
Toniolo, D.
Swinkels, D.W.
Whitfield, J.B.

January 2014

Contains fulltext : 137523.pdf (publisher's version ) (Open Access)Variation in bo...

Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

McLaren, Christine E.
McLachlan, Stela
Garner, Chad P.
Vulpe, Chris D.
Gordeuk, Victor R.
Eckfeldt, John H.
Adams, Paul C.
Acton, Ronald T.
Murray, Joseph A.
Leiendecker-Foster, Catherine
Snively, Beverly M.
Barcellos, Lisa F.
Cook, James D.
McLaren, Gordon D.

June 2012

The existence of multiple inherited disorders of iron metabolism suggests genetic contributions to i...

Frequency distribution of genetic factors influencing iron metabolism in patients with and without hepatic iron accumulation.

Abstract

Extracted data

Frequency distribution of genetic factors influencing iron metabolism in patients with and without hepatic iron accumulation.

Abstract

Extracted data

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