miR-574-59 promoted tumor progression of human lung cancer cells.

<p>(A) 95D cells were transfected with miR-574-5p mimics or the control respectively, and then assayed for their proliferation at the indicated time. (B) 95D cells were transfected with miR-574-5p inhibitor or the control respectively, and then assayed for their proliferation at the indicated time. Error bars indicated standard deviation of triplicate measurements form three independent experiments. (C–F) Groups of eight nude mice were challenged with 2×10⁶ of 95D cells which were stably transfected with miR-574-5p expression vector or miR-574-5p sponge vector respectively, and then assayed for their tumor progression in nude mice at the indicated time. The survival time of tumor bearing mice was also determined. Each bar represents the means (±SD) from eight nude mice in each group.