Expression of OPN, αvβ3 and Pim-1 in NSCLCs and adjacent normal lung tissues.

<p>OPN is expressed in the cytoplasm and appears as either yellow or brown-yellow. Positive expression of OPN was detected in a squamous carcinoma (A) and an adenocarcinoma (B) of the lung but not in the adjacent normal lung tissue (C). αvβ3 is expressed in cell membrane and cytoplasm and appears as either yellow or brown-yellow. αvβ3 is positive in a different squamous carcinoma (D) and an adenocarcinoma (E) of the lung but not in the adjacent normal lung tissue (F). The expression of Pim-1 is predominantly cytoplasmic. Pim-1 is positive in a squamous carcinoma (G) and an adenocarcinoma (H) of the lung but not in the adjacent normal lung tissue (I) (SP 20×10).