Clioquinol reduced TSQ intensity after seizure.

<p>(A) TSQ fluorescence image in the dentate granule cell layer 1 week after sham-operated or seizure-experienced rats. Vesicular TSQ intensity is high in mossy fiber area of dentate granule cell layer in sham operated rats. However, 1 week after seizure the vesicular TSQ fluorescent intensity is decreased in the mossy fiber area. CQ treatment decreased TSQ intensity of mossy fiber area either in sham operated rats or in seizure-experienced rats. Scale bar = 200 µm. (B) A graph represents quantitated intensity of TSQ fluorescent in the hilar area. CQ treated group shows significantly lower TSQ intensity than vehicle treated group in 1 week after seizure (n = 8). Data are means ± SE. *P<0.05.