Acute pancreatitis induces changes in local pancreatic and lung chemokine levels.

<p>Tissue homogenates from pancreas (A, C) and lungs (B, D) were evaluated by ELISA for CXCL1 (A, B) and CCL2 (C, D) levels at the indicated time points. Both CXCL1 and CCL2 levels were significantly elevated in the pancreas (A) and lungs (B) 9, 24 and 48 h after pancreatitis induction compared to sham controls. Bars show mean ± SEM, n = 10 per group. *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 versus sham control, by two-tailed Student <i>t</i>-test.