Inhibition of CaMKKβ prevents baicalin-induced reduction in intracellular lipid accumulation in HeLa cells caused by oleic acid.

<p>Cells were treated with 1 and 5 µM baicalin in the presence of 0.4 mM oleic acid for 24 hr without (open bars) or with pre-incubated with 10 µg/mL STO-609 (solid bars). The control cells were incubated with 1.76% bovine serum albumin (BSA) for 24 h. Intracellular triglyceride (TG, A) and intracellular cholesterol (TC, B) were measured as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047900#s4" target="_blank">Material and Methods</a>. The histogram represents the mean of the percentage of the vehicle control ± SE from at least three independent experiments. * <i>p</i><0.05 compared to BSA control; ^#<i>p</i><0.05 compared to untreated oleic acid control.