Effect of resveratrol (RSV) treatment on cell viability of endothelial cell cultures exposed to oxygen-glucose deprivation (OGD).
- Darren Clark (302548)
- Ursula I. Tuor (302549)
- Roger Thompson (302550)
- Adam Institoris (302552)
- Angela Kulynych (302554)
- Xu Zhang (49484)
- David W. Kinniburgh (302556)
- Ferenc Bari (302557)
- David W. Busija (302558)
- Philip A. Barber (302559)
Publication date
February 2013
DOIAbstract
<p>Improved viability was observed in endothelial cells treated with RSV at low doses (A). A sirtuin-1 antagonist (sirtinol, ST), but not the nitric oxide synthase inhibitor (L-NAME), partially inhibited the RSV protection in endothelial cells (B). * P<0.05; ** P<0.005 different from 0 µM or vehicle (Veh). + P<0.001 different from 0.5 µM RSV alone. (ANOVA with a Student-Newman Keuls test).</p
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