Gene expression differences in HSCs co-cultured on OP9Delta cells with or without Notch signalling.

<p>Real-time RT-PCR results from cord blood (CB) or adult HSCs co-cultured with either control OP9Delta^neg (C) cells, or OP9Delta^pos (+N) cells. Results are depicted as mean expression ratio +SEM relative to housekeeping gene <i>HPRT</i> (<i>n</i> = 3–4 for CB; <i>n</i> = 2–4 for adults). * <i>p</i><0.05 compared with ‘d28 +N’ for CB and adult respectively, unpaired 2-tail <i>t</i>-test. d = day. PTCRA = pre-T cell antigen receptor alpha, GATA3 = GATA binding protein 3, IKZF1 = IKAROS family zinc finger 1, TCF7 = Transcription Factor 7 (T-cell specific, HMG-box), HES1 = Hairy and enhancer of split 1, DTX1 = Deltex homolog 1, MAML1 = Mastermind-like 1, CDKN1B = Cyclin-dependent kinase inhibitor 1B.