Peak of lesion development correlates with source of <i>Leishmania (V.) braziliensis</i> isolates.

<p>C57BL/6J mice were inoculated in the footpad of the left hind leg with 10⁷ promastigotes. Lesion sizes were measured weekly. The lesion size was defined as the difference between the infected and uninfected contralateral footpad from two independent experiments with four mice per group with the exception of isolates RS, SAP, IMG3 and RPL5 (one experiment each). Each point represents the time at which lesion development reached its maximum size for each isolate obtained from mucosal (ML)/mucocutaneous (MCL) lesions or cutaneous lesions (CL). The line represents the mean of the group. Statistical analysis was performed by Students's <i>t</i>-test.