<p>(A) Primary keratinocytes analysed for p63 gene expression in the α6 integrin<sup>high+</sup>/CD44<sup>+</sup> and remainder populations using QRT-PCR. Data represents the log mean fold change of the α6 integrin<sup>high+</sup>/CD44<sup>+</sup> population from the remainder population ± SEM of three replicates, normalised against GAPDH housekeeping gene. Keratinocytes analysed for gene expression after cisplatin (B) or UVB (C) where data represents the log mean fold change from the control (vehicle-only) ± SEM of three replicates, normalised against 28S-r-RNA housekeeping gene. Statistical significance was determined using the paired Student’s t-test, *P<0.05.</p
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
Epidermal human keratinocytes are exposed to a wide range of environmental genotoxic insults, includ...
<p>(A) Primary keratinocytes treated with 50 µg/ml cisplatin, or 1 µM imatinib, or 1 µM imatinib for...
<p>(A) Immunofluorescence histochemistry of frozen normal human skin probed with an antibody against...
<p>(<b>a</b>) FAK protein expression was quantified by western blot analysis in NCTC (3 independent ...
p63 is a transcription factor required for the development and maintenance of ectodermal tissues, ...
<p>Several TGFß inducible genes were measured in human primary keratinocytes in response to TGFß or ...
<p>(A) TPA treated and untreated keratinocytes isolated from trisomic (Ts) and euploid (WT) mice are...
International audiencep63 is a developmentally regulated transcription factor related to p53. It is ...
p63 is a transcription factor required for the development and maintenance of ectodermal tissues in ...
International audiencep63 is a developmentally regulated transcription factor related to p53. It is ...
Recently, the p53 homolog p63 has been implicated in sustaining the epidermal stem cell population. ...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
<p>(<b>a</b>) Quantitative RT-PCR demonstrating the levels of ΔNp63, p73, TSLP, TSLPR and IL-7Rα mRN...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
Epidermal human keratinocytes are exposed to a wide range of environmental genotoxic insults, includ...
<p>(A) Primary keratinocytes treated with 50 µg/ml cisplatin, or 1 µM imatinib, or 1 µM imatinib for...
<p>(A) Immunofluorescence histochemistry of frozen normal human skin probed with an antibody against...
<p>(<b>a</b>) FAK protein expression was quantified by western blot analysis in NCTC (3 independent ...
p63 is a transcription factor required for the development and maintenance of ectodermal tissues, ...
<p>Several TGFß inducible genes were measured in human primary keratinocytes in response to TGFß or ...
<p>(A) TPA treated and untreated keratinocytes isolated from trisomic (Ts) and euploid (WT) mice are...
International audiencep63 is a developmentally regulated transcription factor related to p53. It is ...
p63 is a transcription factor required for the development and maintenance of ectodermal tissues in ...
International audiencep63 is a developmentally regulated transcription factor related to p53. It is ...
Recently, the p53 homolog p63 has been implicated in sustaining the epidermal stem cell population. ...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
<p>(<b>a</b>) Quantitative RT-PCR demonstrating the levels of ΔNp63, p73, TSLP, TSLPR and IL-7Rα mRN...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
p63 is a developmentally regulated transcription factor related to p53. It is involved in the develo...
Epidermal human keratinocytes are exposed to a wide range of environmental genotoxic insults, includ...