M72-expressing OSN population is regenerated 45 days after methimazole treatment.

<p><b>A</b>, Coronal view of control olfactory epithelium is shown. At higher magnification X-gal stained neurons can be observed within the OE and axons can also be seen traversing the LP. <b>B</b>, Almost no X-gal stained neurons can be observed 10 days post lesion. Some axons bundles remain visible along the LP. <b>C</b>, 45 days after methimazole induced lesion, the regenerated olfactory epithelium cannot be distinguished from that of control animals. <b>D</b>, Cell counts in the OE show that the population of M72 neurons is regenerated after methimazole treatment. <b>E</b>, Thickness of olfactory epithelia is significantly decreased 10 days post lesion. Mean ± SEM. Scale bars 400 µm and 80 µm in OE magnifications. *** denotes <i>P</i><0.05.