BMD treatment and induction of transient retinal ischemia.

<p>(A) Diagram for BMD administration before and after ischemic injury. BMD or vehicle were injected by IP for short terms or administrated systemically for 4 weeks using osmotic pumps. (B) IOP elevation in the rat eyes following transient ischemic injury. (B) Mean IOP was 76.1±4.2 mmHg during anterior chamber perfusion with saline. In contrast, mean IOP of contralateral control eyes was 11.2±1.7 mmHg (n = 10). BMD, brimonidine.