ATP release from marginal cells.

<p><b>A</b>. Bafilomycin A1, a specific inhibitor of vacuolar-type H⁺-ATPase, inhibited the release of ATP from marginal cells. <b>B</b>. DDA, a specific inhibitor of adenylate cyclase, increased the release of ATP from marginal cells. <b>C</b>. Extracellular K⁺ concentration increased the release of ATP from marginal cells. <b>D</b>. Influence of thapsigargin, which decreases the intracellular Ca²⁺ concentrations inhibited the release of ATP from marginal cells. <b>E</b>. Extracellular Ca²⁺ concentrations inhibited the release of ATP from marginal cells. <b>F</b>. U73122 which affects the release of Ca²⁺ from intracellular stores inhibited the ATP releasing from marginal cells. <b>G</b>. Aristolochic acid, a PLA₂ inhibitor decreased the release of ATP from marginal cells. The release of ATP was significantly changed after each treatment (n = 8, P<0.05).