Expression of VEGF in the placental beds of women suffering from IUGR/PE or controls and the Immunoreactive Score (IRS) of this staining in the EVT.

<p>Interstitial trophoblast in controls display a stronger immunopositivity for VEGF (A), which are positive for cytokeratin 7 (C) than in early onset IUGR/PE samples (B). In control pregnancies decidual cells showed also a higher VEGF activity (A, arrows) but these cells were not analyzed. Original magnification 200×(bar = 100 µm). (E) The figure represent the mean score + (SEM) of VEGF immunolocalisation to endovascular and interstitial trophoblast cells in both control and early onset IUGR/PE groups. *p<0.05 between the two groups using Student’s t test.