<p><b>A:</b> Cell viability was measured using the CCK-8. After induction with hTNF-α (25 ng/ml) and CHX (10 µg/ml) for 15 hours, the hHO-1 group had a lower percentage of viable cells. <b>B and C:</b> FACS analysis of hTNF-α and CHX-mediated apoptosis in fibroblasts. Apoptosis was analyzed using annexin V staining. The numbers indicate the proportion of apoptotic cells in the NPCCs after 15 hr incubation with hTNF-α and CHX. <b>D:</b> Activities of caspase 3/7 were measured in fibroblasts. Human HO-1 protected transgenic fibroblasts from apoptosis after 15 hr of incubation with hTNF-α and CHX. After Zn(II)PPIX treatment, Ad-hHO-1 increased activity of caspase 3/7. Each experiment was repeated three times. (* p<0.05, ** p<0.01, *** p<0.001,...
<p>72 h after transfection with anti-<i>HNF1A</i> siRNAs, the AsPC-1 and BxPC-3 cells were stained w...
<p>Representative dot plots of the flow cytometric analysis of the Annexin V–FITC/propidium iodide (...
<p>(A) NB4/GFP cells and NB4/GFP-MAD cells were left untreated or were incubated for 15 min with TNF...
<p><b>A:</b> Ad-hHO-1 increased cell viability in H<sub>2</sub>O<sub>2</sub>-treated NPCCs. NPCCs we...
<p><b>A:</b> Western blot analysis for hHO-1 and HA in the hHO-1-Tg fibroblasts using anti-HO-1 (1∶2...
<p>Huh7 and Mahlavu cells were treated with 5, 25 and 50 μg/ml of HH-F3 for 48 hrs. The cells were s...
<p>Cultured GH3 cells were incubated with HN (5 µM) for 2 h before adding TNF-α (50 ng/ml) for 24 h....
<p>(A) U937 cells were treated for 14 and 24 h with 1.4 µg/ml HF or left untreated. Caspase-8, -9 an...
<p><b>A:</b> Expression of the RANTES gene in hHO-1-Tg fibroblasts compared with wild-type fibroblas...
Xenotransplantation using transgenic pigs as an organ source is a promising strategy to overcome sho...
<p><b>A.</b> LH86 and <b>B.</b> Huh7 cells were treated with ABT-263 (0–20 µM) for up to 24 h. Apopt...
<p>A) TUNEL staining for apoptosis in HeLa cells after treatment for 48 h in control, FP and HF grou...
<p>Caspase 3/7 activities were determined in all cell groups after 16h (<b>A</b>) or 24h (<b>B</b>) ...
<p>HepG2 cells were treated with 0.6 mM H<sub>2</sub>O<sub>2</sub> for 8 h. (A) The percentage of ap...
Xenotransplantation using transgenic pigs as an organ source is a promising strategy to overcome sho...
<p>72 h after transfection with anti-<i>HNF1A</i> siRNAs, the AsPC-1 and BxPC-3 cells were stained w...
<p>Representative dot plots of the flow cytometric analysis of the Annexin V–FITC/propidium iodide (...
<p>(A) NB4/GFP cells and NB4/GFP-MAD cells were left untreated or were incubated for 15 min with TNF...
<p><b>A:</b> Ad-hHO-1 increased cell viability in H<sub>2</sub>O<sub>2</sub>-treated NPCCs. NPCCs we...
<p><b>A:</b> Western blot analysis for hHO-1 and HA in the hHO-1-Tg fibroblasts using anti-HO-1 (1∶2...
<p>Huh7 and Mahlavu cells were treated with 5, 25 and 50 μg/ml of HH-F3 for 48 hrs. The cells were s...
<p>Cultured GH3 cells were incubated with HN (5 µM) for 2 h before adding TNF-α (50 ng/ml) for 24 h....
<p>(A) U937 cells were treated for 14 and 24 h with 1.4 µg/ml HF or left untreated. Caspase-8, -9 an...
<p><b>A:</b> Expression of the RANTES gene in hHO-1-Tg fibroblasts compared with wild-type fibroblas...
Xenotransplantation using transgenic pigs as an organ source is a promising strategy to overcome sho...
<p><b>A.</b> LH86 and <b>B.</b> Huh7 cells were treated with ABT-263 (0–20 µM) for up to 24 h. Apopt...
<p>A) TUNEL staining for apoptosis in HeLa cells after treatment for 48 h in control, FP and HF grou...
<p>Caspase 3/7 activities were determined in all cell groups after 16h (<b>A</b>) or 24h (<b>B</b>) ...
<p>HepG2 cells were treated with 0.6 mM H<sub>2</sub>O<sub>2</sub> for 8 h. (A) The percentage of ap...
Xenotransplantation using transgenic pigs as an organ source is a promising strategy to overcome sho...
<p>72 h after transfection with anti-<i>HNF1A</i> siRNAs, the AsPC-1 and BxPC-3 cells were stained w...
<p>Representative dot plots of the flow cytometric analysis of the Annexin V–FITC/propidium iodide (...
<p>(A) NB4/GFP cells and NB4/GFP-MAD cells were left untreated or were incubated for 15 min with TNF...