<p>Modeled time histories of the three cytokine response groups with experimentally derived initial rates of change.</p
During an adaptive immune response, lymphocytes proliferate for ve to twenty cell divisions, then st...
(a) Active migration of agents and passive transport (carried by blood and lymph) of cytokines betwe...
(A) Inferred R over time (black line, left-axis) from the segmented-exponential model fit to rounds ...
Model estimates of relative log(cytokine concentrations) and the corresponding ratios of change betw...
<p>Pattern of change in serum cytokine or chemokine concentrations over time for the T1D, IA, and co...
<p>A. Standard deviation for leukocytes response as a function of time, B. Standard deviation for ΔM...
<p>Summary of parameter values governing release rates, cytokine sensitivities, migration rates, pro...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
In biological systems, reactions on different time scales exist and need to be considered for the an...
Scenario 1 of the simple reaction cycle model: Time course of state variables (Panel A), and normali...
Scenario 2 (left) & 3 (right) of the simple reaction model: Time course of state variables (Panels A...
<p>The progression of adaptations induced by a treatment intervention is predicted by identifying ne...
Signal integration determines cell fate on the cellular level, affects cognitive processes and affec...
T-cell primary activation is a key event in the initiation of the adaptive immune response. Quantify...
<p>(<b>a</b>) Change of concentrations for all 15 cytokines in the microenvironment over a period of...
During an adaptive immune response, lymphocytes proliferate for ve to twenty cell divisions, then st...
(a) Active migration of agents and passive transport (carried by blood and lymph) of cytokines betwe...
(A) Inferred R over time (black line, left-axis) from the segmented-exponential model fit to rounds ...
Model estimates of relative log(cytokine concentrations) and the corresponding ratios of change betw...
<p>Pattern of change in serum cytokine or chemokine concentrations over time for the T1D, IA, and co...
<p>A. Standard deviation for leukocytes response as a function of time, B. Standard deviation for ΔM...
<p>Summary of parameter values governing release rates, cytokine sensitivities, migration rates, pro...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
In biological systems, reactions on different time scales exist and need to be considered for the an...
Scenario 1 of the simple reaction cycle model: Time course of state variables (Panel A), and normali...
Scenario 2 (left) & 3 (right) of the simple reaction model: Time course of state variables (Panels A...
<p>The progression of adaptations induced by a treatment intervention is predicted by identifying ne...
Signal integration determines cell fate on the cellular level, affects cognitive processes and affec...
T-cell primary activation is a key event in the initiation of the adaptive immune response. Quantify...
<p>(<b>a</b>) Change of concentrations for all 15 cytokines in the microenvironment over a period of...
During an adaptive immune response, lymphocytes proliferate for ve to twenty cell divisions, then st...
(a) Active migration of agents and passive transport (carried by blood and lymph) of cytokines betwe...
(A) Inferred R over time (black line, left-axis) from the segmented-exponential model fit to rounds ...
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