<p>The mRNA (A) and protein (B) expression levels of TGF-β<sub>1</sub> were significantly increased in the group of mice treated with CCl<sub>4</sub> (50 µg/kg) when compared with the control group. Preadministration of polydatin (100 mg/kg) for 5 consecutive days enhanced TGF-β<sub>1</sub> expression levels further. <sup>ΔΔ</sup> P<0.01 compared with the control group; **P<0.01 compared with the CCl4 group. Data are expressed as the mean ± SD. 6 samples in each group were used for mRNA analysis, and 4 samples in each group for protein analysis.</p
<p>C57BL/6 mice were fed a normal diet and drinking water supplemented with 1% 4-PBA (wt/wt) for 2 w...
Depression is a prevalent psychiatric disorder with a significant health impact and economic burden ...
<p>C57BL/6 mice fed a normal diet were injected intraperitoneally with tributyrin (0.5 g/kg BW) or v...
<p>Intraperitoneal injection of CCl<sub>4</sub> (50 µl/kg) obviously decreased the hepatic activitie...
<p>The NF-κB activity dramatically increased in the CCl4 group of mice (50 µg/kg CCl<sub>4</sub>), b...
<p>Serum ALT and AST levels were markedly enhanced after 16 h of intraperitoneal injection of CCl4 (...
<p>Pretreatment with polydatin for 5 consecutive days evidently decreased mRNA expression levels of ...
Polydatin, a small molecule from Polygonum cuspidatum, has many biological functions, particularly a...
<p>(A) Hepatic levels of <i>TGF β1</i> mRNA from ND, MCD and LPS-injected MCD mice in WT or Tlr4<sup...
<p><b>(</b>A) Mouse MCs were cultured in the presence or absence of 1 ng/ml TGF-β for the indicated ...
(A) LLC-PK1 cells and (C) dGBECs were treated with the indicated TGF-ß1 concentrations for 12 h, and...
Pharmacological concentrations of biotin have pleiotropic effects. Several reports have documented t...
<p>CCl4 treatment for 16 h was responsible for extensive degeneration and necrosis in the liver tiss...
<p>The protein and mRNA expression were a determined via Western blot and RT-PCR, respectively. Valu...
<p>Co-incubation with polydatin (1, 3, or 10 μmol/L) in HG-stimulated aortas markedly upregulated th...
<p>C57BL/6 mice were fed a normal diet and drinking water supplemented with 1% 4-PBA (wt/wt) for 2 w...
Depression is a prevalent psychiatric disorder with a significant health impact and economic burden ...
<p>C57BL/6 mice fed a normal diet were injected intraperitoneally with tributyrin (0.5 g/kg BW) or v...
<p>Intraperitoneal injection of CCl<sub>4</sub> (50 µl/kg) obviously decreased the hepatic activitie...
<p>The NF-κB activity dramatically increased in the CCl4 group of mice (50 µg/kg CCl<sub>4</sub>), b...
<p>Serum ALT and AST levels were markedly enhanced after 16 h of intraperitoneal injection of CCl4 (...
<p>Pretreatment with polydatin for 5 consecutive days evidently decreased mRNA expression levels of ...
Polydatin, a small molecule from Polygonum cuspidatum, has many biological functions, particularly a...
<p>(A) Hepatic levels of <i>TGF β1</i> mRNA from ND, MCD and LPS-injected MCD mice in WT or Tlr4<sup...
<p><b>(</b>A) Mouse MCs were cultured in the presence or absence of 1 ng/ml TGF-β for the indicated ...
(A) LLC-PK1 cells and (C) dGBECs were treated with the indicated TGF-ß1 concentrations for 12 h, and...
Pharmacological concentrations of biotin have pleiotropic effects. Several reports have documented t...
<p>CCl4 treatment for 16 h was responsible for extensive degeneration and necrosis in the liver tiss...
<p>The protein and mRNA expression were a determined via Western blot and RT-PCR, respectively. Valu...
<p>Co-incubation with polydatin (1, 3, or 10 μmol/L) in HG-stimulated aortas markedly upregulated th...
<p>C57BL/6 mice were fed a normal diet and drinking water supplemented with 1% 4-PBA (wt/wt) for 2 w...
Depression is a prevalent psychiatric disorder with a significant health impact and economic burden ...
<p>C57BL/6 mice fed a normal diet were injected intraperitoneally with tributyrin (0.5 g/kg BW) or v...