Standard analyses and reporting of clinical and virological endpoints in early-phase trials of dengue therapeutics.

*<p>Comparisons of laboratory and virological features between study groups should be adjusted for the baseline value, the day of illness on admission, and serotype/serology (for virological features) to maximize power.</p>a<p>AUC calculated based on the trapezoidal rule with values below the limit of detection replaced by half of the detection limit.