Immune responses to the newly identified CD8 peptides after rechallenge.

<p>Mice were primed with X31 virus (3×10⁵ EID₅₀) and rested for 42 days before challenged with a lethal dose of CA/E3/09 virus (3000 PFU). At day 6 after the rechallenge, the IFN-γ responses for identified CA/E3/09 CD8 peptides including CANP399, CANP41, CANP55, CANP130, CANP296 and CAPA439 were measured by ELISPOT assay (A) Data are representative of three independent experiments.