Effect of various cytokines, in comparison with <i>γ-Mtb</i>, on induction of TF in macrophages.

<p>MDMs were treated with IFN-γ (100 ng/ml), TNF-α (20 ng/ml), IL1-β (20 ng/ml), IL-6 (20 ng/ml) or IL-8 (20 ng/ml) for 9 h. In parallel, MDMs were treated with γ-<i>Mtb</i> (10 µg/ml). Cell surface TF activity was determined in factor X activation assay. * indicates significant difference compared to untreated control (P<0.05); # denotes significant difference compared to γ-<i>Mtb</i> treated cells (P<0.05). Data are mean ± SEM (n = 3).