CPEE decreases the MMP-9 activities and protein expression in lung tissues of mice.

<p>The protein of supernatants was loaded for gelatin zymography (60 µg/lane). SDS−PAGE zymography was performed according to the method of Heussen and Dowdle (1980). (A) MMP-9 activities (B) MMP-9 protein expression. NC; normal control mice treated with PBS only; OVA; OVA-sensitized/challenged mice; Mon; Montelukast (30 mg/kg) + OVA-sensitized/challenged mice; CPEE-1; CPEE (100 mg/kg) + OVA-sensitized/challenged mice; CPEE-2; CPEE (200 mg/kg) + OVA-sensitized/challenged mice.