Serum pentraxin 3 (PTX3) concentrations in 50 patients with pulmonary arterial hypertension (PAH) and 100 healthy controls, and their correlation with serum concentrations of other biomarkers.

<p>A: Comparison of PTX3 concentrations in PAH patients and healthy controls. Mean plasma PTX3 concentrations were 4.40±0.37 and 1.94±0.09 ng/mL in the controls and PAH patients, respectively. B: Distribution of log-transformed PTX3 concentrations in PAH patients and healthy controls. C: Log-transformed PTX3 concentrations were significantly higher in patients with PAH than in healthy controls (1.34±0.07 vs. 0.55±0.05 log ng/mL, respectively; <i>P</i><0.001). D, E: There was no correlation between plasma concentrations of PTX3 and either B-type natriuretic peptide (BNP; <i>r</i> = 0.33, <i>P</i> = 0.02) or C-reactive protein (CRP; <i>r</i> = 0.21, <i>P</i> = 0.14) in PAH patients.