MUC1.Tg mice appeared to elicit MUC1-specific peripheral tolerance.

<p>T cells from mice vaccinated with MUC1 DNA or T cells from mice immunized with control vectors (3×10⁶ cells) were mixed with B16-F10-MUC1 cells (5×10⁴ cells) and subcutaneously injected into naïve B6 or MUC1.Tg mice. Survival rates of the mice are shown. Statistical analysis was performed using the log rank test (n.s.: not significant). A representative result from three independent experiments is shown.