Immunization of mice with DCs loaded with CD11c-scFv-IDRgag provides a better control of acute viremia.

<p>(<b>A</b>) When animals were immunized twice with bmDCs loaded with CD11c-scFv-IDRgag or control-scFv-IDRgag in one week interval and challenged one week after the second immunization, animals immunized with bmDCs loaded with CD11c-scFv-IDRgag were protected significantly better against FV induced splenomegaly, which correlated with a significantly lower frequency of infected cells in the spleen (<b>B</b>). Data were analyzed by one-way ANOVA with Tukey’s multiple comparison test. Significance was labeled with * if p<0.05, ** if p<0.01, *** if p<0.001. Data represents results from one experiment.