<p>The tumor model set up was the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045571#pone-0045571-g009" target="_blank">Figure 9</a>. <b>a</b>. The mean tumor growth curves ± SE derived from five individual mice in response to treatment with vehicle (control), FL118 or irinotecan. <b>b</b>. The mean mouse body weight change ± SE derived from five individual mice in response to treatment with vehicle (control), FL118 or irinotecan. <b>c</b>, <b>d</b> and <b>e</b>. Tumor growth curves from individual tumor xenografts in response to treatment with vehicle (<b>c</b>), irinotecan (<b>d</b>) or FL118 (<b>e</b>). The treatment schedule was weekly × 4 as indicated by arrows. The dose used for irinotecan and FL1...
(A) HuH6 cells (2.5 x 106 cells in 25% Matrigel) were injected subcutaneously into the right flank o...
This study was undertaken to investigate the potential role of xenografts established from human hea...
<p>Female nude mice with xenograft MDA-MB-231 tumor tumors received various treatments for 38 days s...
*<p>Tumor size was measured daily for the first 4 weeks and then 3–4 time a week. The data shown her...
<p><b>a</b>. Results from the human head and neck FaDu tumor xenograft mouse model. <b>b</b>. Result...
<p>(A) RD xenograft tumor growth curve in BALB/C nude mice. The mice were injected with the followin...
<p>Mice bearing COLO 205 xenografts (∼200 mm<sup>3</sup>) were randomly assigned into treatment grou...
<p>Combination therapy was given i. p. in two cycles (d0 - d3 & d21 - d24): On the first day the ani...
Background: The purpose of this study was to assess the efficacy of three chemotherapeutic agents bo...
<p>(<b>A</b>) OEC-M1 tumor-bearing mice were administered s.c. with vehicle control (◊), 15 mg/kg (△...
<p><b>A</b>. DBDX showed stronger antitumor activity than GEM in PG xenograft model. <b>B</b>. DBDX ...
<p>(A) HT29 and HCT116 tumor xenograft growth curves. Animals were treated for 28 days with vehicles...
<p><b>a</b>, Mice bearing BT483-derived breast cancer xenografts with average tumor size of ∼75 mm<s...
<p>A to D, Nude mice bearing established HepG2 tumors were treated with irinotecan at 1 mg/kg every ...
<p>Solid tumor was induced in Swiss albino mice by injecting EAC cells. Six doses of <b>4a</b> and L...
(A) HuH6 cells (2.5 x 106 cells in 25% Matrigel) were injected subcutaneously into the right flank o...
This study was undertaken to investigate the potential role of xenografts established from human hea...
<p>Female nude mice with xenograft MDA-MB-231 tumor tumors received various treatments for 38 days s...
*<p>Tumor size was measured daily for the first 4 weeks and then 3–4 time a week. The data shown her...
<p><b>a</b>. Results from the human head and neck FaDu tumor xenograft mouse model. <b>b</b>. Result...
<p>(A) RD xenograft tumor growth curve in BALB/C nude mice. The mice were injected with the followin...
<p>Mice bearing COLO 205 xenografts (∼200 mm<sup>3</sup>) were randomly assigned into treatment grou...
<p>Combination therapy was given i. p. in two cycles (d0 - d3 & d21 - d24): On the first day the ani...
Background: The purpose of this study was to assess the efficacy of three chemotherapeutic agents bo...
<p>(<b>A</b>) OEC-M1 tumor-bearing mice were administered s.c. with vehicle control (◊), 15 mg/kg (△...
<p><b>A</b>. DBDX showed stronger antitumor activity than GEM in PG xenograft model. <b>B</b>. DBDX ...
<p>(A) HT29 and HCT116 tumor xenograft growth curves. Animals were treated for 28 days with vehicles...
<p><b>a</b>, Mice bearing BT483-derived breast cancer xenografts with average tumor size of ∼75 mm<s...
<p>A to D, Nude mice bearing established HepG2 tumors were treated with irinotecan at 1 mg/kg every ...
<p>Solid tumor was induced in Swiss albino mice by injecting EAC cells. Six doses of <b>4a</b> and L...
(A) HuH6 cells (2.5 x 106 cells in 25% Matrigel) were injected subcutaneously into the right flank o...
This study was undertaken to investigate the potential role of xenografts established from human hea...
<p>Female nude mice with xenograft MDA-MB-231 tumor tumors received various treatments for 38 days s...