Crystal structure of the winged-helix domain of human NFRKB.

<p>(<b>A</b>) Ribbon diagram of the human NFRKB_WHL domain (residues 370–495) structure is color-coded from N-terminus (blue) to C-terminus (red). Helices α1–α4, β-strands β1–β3 and 3₁₀ helixes η1–η3 are indicated. The dashed line between β3 and α4 corresponds to three disordered residues that were omitted from the model. (<b>B</b>) Protein sequence of the NFRKB_WHL domain annotated with the corresponding secondary structure elements. The dashed lines indicate residues that were in the construct, but are not in the refined model due to lack of interpretable electron density. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043761#pone-0043761-g001" target="_blank">Figure 1B</a> was prepared with ESPript <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043761#pone.0043761-Gouet1" target="_blank">[40]</a>.