<p>Using the OCR traces shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044610#pone-0044610-g005" target="_blank">Figure 5</a> A–C, maximal OCR, reserve capacity, and non-mitochondrial OCR were determined. Maximal OCR for rotenone (A), MPP<sup>+</sup> (B), and 6-OHDA (C), reserve capacity for rotenone (D), MPP<sup>+</sup> (E), and 6-OHDA (F), and non-mitochondrial OCR for rotenone (G), MPP<sup>+</sup> (H), and 6-OHDA (I) are shown. Data are expressed as percent normalized to OCR before injection of rotenone, MPP<sup>+</sup>, and 6-OHDA. Data = mean ± SEM, n = 3. *<i>p</i><0.05, Student <i>t</i>-test compared to 0 µM treatment.</p
<p>Vector control and 14-3-3θ cells were treated with varying doses of rotenone or 10 µM carbonyl cy...
<p><b>a) Less Bax translocated to mitochondria in 14-3-3θ cells in response to rotenone.</b> After t...
The objectives of the study were to explore the mechanism of rotenone-induced cell damage and to exa...
<p>Changes in basal OCR after rotenone (A), MPP<sup>+</sup> (B), and 6-OHDA (C) are shown and are ex...
<p>After exposure to rotenone (A), MPP<sup>+</sup> (B), and 6-OHDA (C) for 2 hr, OCRs were measured ...
<p>Using the XF24 analyzer, the mitochondrial oxygen consumption rate (OCR) was determined for 4 bas...
<p><b>A)</b> 100 nM rotenone decreased the baseline oxygen consumption rate (OCR) and maximal respir...
<p>(A) OCR recording at baseline and subsequent treatment of MB or its derivatives, oligomycin, FCCP...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (...
<p>A. cells were treated with 0~100 μmol/L (μM) rotenone for 24 hours. Cell viability was measured a...
Rotenone, an organic pesticide and potent mitochondrial complex I inhibitor, causes Parkinson-like n...
<p>(A) The mitochondrial complex I inhibitor rotenone (40 μM) significantly reduced mitochondrial me...
<p>Vector control and 14-3-3θ cells were treated with varying doses of rotenone or 10 µM carbonyl cy...
<p><b>a) Less Bax translocated to mitochondria in 14-3-3θ cells in response to rotenone.</b> After t...
The objectives of the study were to explore the mechanism of rotenone-induced cell damage and to exa...
<p>Changes in basal OCR after rotenone (A), MPP<sup>+</sup> (B), and 6-OHDA (C) are shown and are ex...
<p>After exposure to rotenone (A), MPP<sup>+</sup> (B), and 6-OHDA (C) for 2 hr, OCRs were measured ...
<p>Using the XF24 analyzer, the mitochondrial oxygen consumption rate (OCR) was determined for 4 bas...
<p><b>A)</b> 100 nM rotenone decreased the baseline oxygen consumption rate (OCR) and maximal respir...
<p>(A) OCR recording at baseline and subsequent treatment of MB or its derivatives, oligomycin, FCCP...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
International audienceThe permeability transition pore (PTP) is a mitochondrial inner membrane Ca(2+...
The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (...
<p>A. cells were treated with 0~100 μmol/L (μM) rotenone for 24 hours. Cell viability was measured a...
Rotenone, an organic pesticide and potent mitochondrial complex I inhibitor, causes Parkinson-like n...
<p>(A) The mitochondrial complex I inhibitor rotenone (40 μM) significantly reduced mitochondrial me...
<p>Vector control and 14-3-3θ cells were treated with varying doses of rotenone or 10 µM carbonyl cy...
<p><b>a) Less Bax translocated to mitochondria in 14-3-3θ cells in response to rotenone.</b> After t...
The objectives of the study were to explore the mechanism of rotenone-induced cell damage and to exa...