<i>axin1</i> but not <i>axin1(Q162A)</i> rescues anterior defects in Axin1-depleted embryos.

<p>(<b>A–D′</b>) Representative phenotypes of control and Axin1-depleted zebrafish embryos. (<b>A</b>) control uninjected embryo, (<b>B</b>) Axin1-depleted embryo (4 ng <i>axin1</i>-MO), (<b>C</b>) MO injected embryo coinjected with 25 pg <i>axin1</i> mRNA, (<b>D</b>) MO injected embryo coinjected with 25 pg <i>axin1(Q162A)</i> mRNA. (<b>E</b>) Summary table of morphological defects.