Predictive values for SVR among the DITTO-HCV genotype 1 patients included in the study.

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and baseline HCV viral load.

Barham K. Abu Dayyeh (342522)
Namrata Gupta (229166)
Kenneth E. Sherman (171505)
Paul I. W. de Bakker (61332)
Raymond T. Chung (214536)

February 2013

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and b...

On-treatment responses of the DITTO-HCV genotype 1 patients grouped below or above the sCD26 600 ng/mL cut-off concentration prior to start of therapy.

Jonas Söderholm (355580)
Jesper Waldenström (380139)
Galia Askarieh (321575)
Massimo Pilli (179843)
Pierre-Yves Bochud (205597)
Francesco Negro (205592)
Jean-Michel Pawlotsky (355584)
Stefan Zeuzem (22856)
Carlo Ferrari (179895)
Gunnar Norkrans (321586)
Rune Wejstål (380140)
Johan Westin (321583)
Avidan U. Neumann (255364)
Bart L. Haagmans (253561)
Magnus Lindh (315102)
Gabriele Missale (139494)
Kristoffer Hellstrand (321584)
Martin Lagging (321589)

February 2013

Median (range) or individuals (percent). Statistics using aMann-Whitney U test ...

Baseline demographic and immuno-virological characteristics of patients according SVR.

Giulia Marchetti (131632)
Paola Nasta (182198)
Francesca Bai (131622)
Francesca Gatti (182206)
Giusi Maria Bellistrì (182213)
Camilla Tincati (182218)
Federica Borghi (182223)
Giampiero Carosi (182226)
Massimo Puoti (182231)
Antonella d'Arminio Monforte (182235)

February 2012

LEGEND. Data are presented as *median, (IQR) and °absolute number, (%). Differences betwee...

Predictive values for SVR in patients infected with HCV genotype 1 (n = 79).

Tatsuo Miyamura (337726)
Tatsuo Kanda (234184)
Shingo Nakamoto (337728)
Shuang Wu (148427)
Keiichi Fujiwara (234194)
Fumio Imazeki (234191)
Osamu Yokosuka (234198)

February 2013

Nuclear-STAT1, STAT1-nuclear translocation; PPV, positive predictive value; NPV, negative predict...

Sensitivity, specificity, positive and negative predictive values of the likelihood achieving SVR among patients infected with HCV genotype 1 (n = 170).

Martin Lagging (321589)
Galia Askarieh (321575)
Francesco Negro (205592)
Stephanie Bibert (316131)
Jonas Söderholm (355580)
Johan Westin (321583)
Magnus Lindh (315102)
Ana Romero (355582)
Gabriele Missale (139494)
Carlo Ferrari (179895)
Avidan U. Neumann (255364)
Jean-Michel Pawlotsky (355584)
Bart L. Haagmans (253561)
Stefan Zeuzem (22856)
Pierre-Yves Bochud (205597)
Kristoffer Hellstrand (321584)

February 2013

Sensitivity, specificity, positive and negative predictive values of the likelihood achieving SVR...

Odds ratio (OR) and stepwise binary logistic regression analysis identifying pretreatment factors independently predictive of SVR in DITTO-HCV genotype 1 patients.

Jonas Söderholm (355580)
Jesper Waldenström (380139)
Galia Askarieh (321575)
Massimo Pilli (179843)
Pierre-Yves Bochud (205597)
Francesco Negro (205592)
Jean-Michel Pawlotsky (355584)
Stefan Zeuzem (22856)
Carlo Ferrari (179895)
Gunnar Norkrans (321586)
Rune Wejstål (380140)
Johan Westin (321583)
Avidan U. Neumann (255364)
Bart L. Haagmans (253561)
Magnus Lindh (315102)
Gabriele Missale (139494)
Kristoffer Hellstrand (321584)
Martin Lagging (321589)

February 2013

OR with 95% confidence intervals for the factors analyzed, with values going from low to high or ...

Rates of SVR according to marker genotypes.

Luis M. Real (166765)
Karin Neukam (584773)
Rocío Herrero (584774)
Josep M. Guardiola (584775)
Thomas Reiberger (143056)
Antonio Rivero-Juarez (4003328)
Juliana Salazar (398495)
Mattias Mandorfer (584776)
Dolores Merino (584777)
Vicente Soriano (584778)
Antonio Rivero (189661)
Juan Macías (2198092)
Juan A. Pineda (189667)
Antonio Caruz (51665)

April 2014

A: in HCV-1 infected patients and B: in HCV-4 infected patients. n/N: number of patients who achi...

SVR12 according to baseline patient characteristics and on-treatment HCV viral decline.

Chen-Hua Liu (292603)
Chun-Jen Liu (289145)
Tung-Hung Su (289150)
Hung-Chih Yang (138284)
Chun-Ming Hong (6111491)
Tai-Chung Tseng (289147)
Pei-Jer Chen (53402)
Ding-Shinn Chen (53409)
Jia-Horng Kao (85991)

December 2018

SVR12 according to baseline patient characteristics and on-treatment HCV viral decline.</p

Comparison of Positive Predictive Value (PPV) for Sustained Virological Response (SVR) of viral decline of ≥ or < than 1.5 log IU/mL at week 2 after start of therapy relative to IL28B genotype (CC versus non-CC) (Figure 1A), liver fibrosis stage (F0–F2 versus F3–F4) (Figure 1B), HCV genotype (1a versus 1b) (Figure 1C), and baseline HCV viral load (≥600,000 IU/mL versus <600,000 IU/mL) (Figure 1D).

Antonio Rivero-Juarez (4003328)
Luis F. López-Cortés (189634)
Angela Camacho (299566)
Almudena Torres-Cornejo (189653)
Ana Gordon (580622)
Rosa Ruiz-Valderas (189639)
Julian Torre-Cisneros (299567)
Juan A. Pineda (189667)
Pompeyo Viciana (189676)
Antonio Rivero (189661)

June 2014

P value was obtained using Fisher’s exact test or the chi-square test.</p

Cumulative rates of SVR stratified by EVR using the Kaplan-Meier method.

Nobuhiro Harada (3410)
Sumihito Tamura (530879)
Yasuhiko Sugawara (530880)
Junichi Togashi (530881)
Takeaki Ishizawa (530882)
Junichi Kaneko (530883)
Taku Aoki (530884)
Yoshihiro Sakamoto (530885)
Kiyoshi Hasegawa (530886)
Tomohiro Tanaka (513251)
Noriyo Yamashiki (465622)
Norihiro Kokudo (530887)

March 2014

A. HCV RNA genotype non-1b, B. HCV RNA genotype 1b. Abbreviations: SVR, sustained viral response;...

Factors predicted SVR to Peg-IFN/RBV treatment in genotype I chronic hepatitis C patients by univariate and multivariate Logistic regression analysis.

Chun-Yen Lin (298233)
Ji-Yih Chen (298235)
Tsung-Nan Lin (353858)
Wen-Juei Jeng (298232)
Chien-Hao Huang (298239)
Chang-Wen Huang (298237)
Su-Wei Chang (231505)
I-Shyan Sheen (44643)

February 2013

UV: univariate logistic regression analysis. MV: multivariate logistic regression analysis.<p...

Lagging Martin
Askarieh Galia
Negro Francesco
Bibert Stephanie
Söderholm Jonas
Westin Johan
Lindh Magnus
Romero Ana
Missale Gabriele
Ferrari Carlo
Neumann Avidan U.
Pawlotsky Jean-Michel
Haagmans Bart L.
Zeuzem Stefan
Bochud Pierre-Yves
Hellstrand Kristoffer

February 2011

predict spontaneous resolution of HCV infection and outcome of treatment among HCV genotype 1 infec...

Cumulative rates of SVR based on the Kaplan-Meier method.

Nobuhiro Harada (3410)
Sumihito Tamura (530879)
Yasuhiko Sugawara (530880)
Junichi Togashi (530881)
Takeaki Ishizawa (530882)
Junichi Kaneko (530883)
Taku Aoki (530884)
Yoshihiro Sakamoto (530885)
Kiyoshi Hasegawa (530886)
Tomohiro Tanaka (513251)
Noriyo Yamashiki (465622)
Norihiro Kokudo (530887)

March 2014

A. Stratified by EVR, B. HCV genotype, C. major allele (TT) in the recipient, and D. major allele...

SVR and RVR rates according to INF-L3 and HCV genotype.

Steffen B. Wiegand (642890)
Benjamin Heidrich (345028)
Simone Susser (48294)
Magdalena Rogalska-Taranta (285584)
Jörg Petersen (76825)
Klaus H. W. Böker (642894)
Natalia Grigorian (839704)
Ralph Link (642892)
Uwe Naumann (642896)
Christine John (839705)
Stefan Lueth (839706)
Peter Malfertheiner (144819)
Michael P. Manns (92947)
Heiner Wedemeyer (32361)
Christoph Sarrazin (48298)
Markus Cornberg (32357)

January 2016

(A) SVR rates in relation to IFNL3 genotype (PP analysis). (B) RVR rates in relation to IF...

Univariate and multivariate analyses for identification of independent predictive factors for SVR in HCV-2a- and -2b-infected patients treated with PEG-IFN/RBV therapy.

Ahmed El-Shamy (185397)
Ikuo Shoji (127861)
Soo-Ryang Kim (185402)
Yoshihiro Ide (185406)
Susumu Imoto (185410)
Lin Deng (127858)
Seitetsu Yoon (185415)
Takashi Fujisawa (185418)
Satoshi Tani (185420)
Yoshihiko Yano (185421)
Yasushi Seo (185424)
Takeshi Azuma (153452)
Hak Hotta (127864)

February 2012

Abbreviations: SVR, sustained virological response; IRRDR[2a], interferon/ribavirin resistance-de...

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and baseline HCV viral load.

Barham K. Abu Dayyeh (342522)
Namrata Gupta (229166)
Kenneth E. Sherman (171505)
Paul I. W. de Bakker (61332)
Raymond T. Chung (214536)

February 2013

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and b...

On-treatment responses of the DITTO-HCV genotype 1 patients grouped below or above the sCD26 600 ng/mL cut-off concentration prior to start of therapy.

Jonas Söderholm (355580)
Jesper Waldenström (380139)
Galia Askarieh (321575)
Massimo Pilli (179843)
Pierre-Yves Bochud (205597)
Francesco Negro (205592)
Jean-Michel Pawlotsky (355584)
Stefan Zeuzem (22856)
Carlo Ferrari (179895)
Gunnar Norkrans (321586)
Rune Wejstål (380140)
Johan Westin (321583)
Avidan U. Neumann (255364)
Bart L. Haagmans (253561)
Magnus Lindh (315102)
Gabriele Missale (139494)
Kristoffer Hellstrand (321584)
Martin Lagging (321589)

February 2013

Median (range) or individuals (percent). Statistics using aMann-Whitney U test ...

Baseline demographic and immuno-virological characteristics of patients according SVR.

Giulia Marchetti (131632)
Paola Nasta (182198)
Francesca Bai (131622)
Francesca Gatti (182206)
Giusi Maria Bellistrì (182213)
Camilla Tincati (182218)
Federica Borghi (182223)
Giampiero Carosi (182226)
Massimo Puoti (182231)
Antonella d'Arminio Monforte (182235)

February 2012

LEGEND. Data are presented as *median, (IQR) and °absolute number, (%). Differences betwee...

Predictive values for SVR in patients infected with HCV genotype 1 (n = 79).

Tatsuo Miyamura (337726)
Tatsuo Kanda (234184)
Shingo Nakamoto (337728)
Shuang Wu (148427)
Keiichi Fujiwara (234194)
Fumio Imazeki (234191)
Osamu Yokosuka (234198)

February 2013

Nuclear-STAT1, STAT1-nuclear translocation; PPV, positive predictive value; NPV, negative predict...

Sensitivity, specificity, positive and negative predictive values of the likelihood achieving SVR among patients infected with HCV genotype 1 (n = 170).

Martin Lagging (321589)
Galia Askarieh (321575)
Francesco Negro (205592)
Stephanie Bibert (316131)
Jonas Söderholm (355580)
Johan Westin (321583)
Magnus Lindh (315102)
Ana Romero (355582)
Gabriele Missale (139494)
Carlo Ferrari (179895)
Avidan U. Neumann (255364)
Jean-Michel Pawlotsky (355584)
Bart L. Haagmans (253561)
Stefan Zeuzem (22856)
Pierre-Yves Bochud (205597)
Kristoffer Hellstrand (321584)

February 2013

Sensitivity, specificity, positive and negative predictive values of the likelihood achieving SVR...

Odds ratio (OR) and stepwise binary logistic regression analysis identifying pretreatment factors independently predictive of SVR in DITTO-HCV genotype 1 patients.

Jonas Söderholm (355580)
Jesper Waldenström (380139)
Galia Askarieh (321575)
Massimo Pilli (179843)
Pierre-Yves Bochud (205597)
Francesco Negro (205592)
Jean-Michel Pawlotsky (355584)
Stefan Zeuzem (22856)
Carlo Ferrari (179895)
Gunnar Norkrans (321586)
Rune Wejstål (380140)
Johan Westin (321583)
Avidan U. Neumann (255364)
Bart L. Haagmans (253561)
Magnus Lindh (315102)
Gabriele Missale (139494)
Kristoffer Hellstrand (321584)
Martin Lagging (321589)

February 2013

OR with 95% confidence intervals for the factors analyzed, with values going from low to high or ...

Rates of SVR according to marker genotypes.

Luis M. Real (166765)
Karin Neukam (584773)
Rocío Herrero (584774)
Josep M. Guardiola (584775)
Thomas Reiberger (143056)
Antonio Rivero-Juarez (4003328)
Juliana Salazar (398495)
Mattias Mandorfer (584776)
Dolores Merino (584777)
Vicente Soriano (584778)
Antonio Rivero (189661)
Juan Macías (2198092)
Juan A. Pineda (189667)
Antonio Caruz (51665)

April 2014

A: in HCV-1 infected patients and B: in HCV-4 infected patients. n/N: number of patients who achi...

SVR12 according to baseline patient characteristics and on-treatment HCV viral decline.

Chen-Hua Liu (292603)
Chun-Jen Liu (289145)
Tung-Hung Su (289150)
Hung-Chih Yang (138284)
Chun-Ming Hong (6111491)
Tai-Chung Tseng (289147)
Pei-Jer Chen (53402)
Ding-Shinn Chen (53409)
Jia-Horng Kao (85991)

December 2018

SVR12 according to baseline patient characteristics and on-treatment HCV viral decline.</p

Comparison of Positive Predictive Value (PPV) for Sustained Virological Response (SVR) of viral decline of ≥ or < than 1.5 log IU/mL at week 2 after start of therapy relative to IL28B genotype (CC versus non-CC) (Figure 1A), liver fibrosis stage (F0–F2 versus F3–F4) (Figure 1B), HCV genotype (1a versus 1b) (Figure 1C), and baseline HCV viral load (≥600,000 IU/mL versus <600,000 IU/mL) (Figure 1D).

Antonio Rivero-Juarez (4003328)
Luis F. López-Cortés (189634)
Angela Camacho (299566)
Almudena Torres-Cornejo (189653)
Ana Gordon (580622)
Rosa Ruiz-Valderas (189639)
Julian Torre-Cisneros (299567)
Juan A. Pineda (189667)
Pompeyo Viciana (189676)
Antonio Rivero (189661)

June 2014

P value was obtained using Fisher’s exact test or the chi-square test.</p

Cumulative rates of SVR stratified by EVR using the Kaplan-Meier method.

Nobuhiro Harada (3410)
Sumihito Tamura (530879)
Yasuhiko Sugawara (530880)
Junichi Togashi (530881)
Takeaki Ishizawa (530882)
Junichi Kaneko (530883)
Taku Aoki (530884)
Yoshihiro Sakamoto (530885)
Kiyoshi Hasegawa (530886)
Tomohiro Tanaka (513251)
Noriyo Yamashiki (465622)
Norihiro Kokudo (530887)

March 2014

A. HCV RNA genotype non-1b, B. HCV RNA genotype 1b. Abbreviations: SVR, sustained viral response;...

Factors predicted SVR to Peg-IFN/RBV treatment in genotype I chronic hepatitis C patients by univariate and multivariate Logistic regression analysis.

Chun-Yen Lin (298233)
Ji-Yih Chen (298235)
Tsung-Nan Lin (353858)
Wen-Juei Jeng (298232)
Chien-Hao Huang (298239)
Chang-Wen Huang (298237)
Su-Wei Chang (231505)
I-Shyan Sheen (44643)

February 2013

UV: univariate logistic regression analysis. MV: multivariate logistic regression analysis.<p...

Lagging Martin
Askarieh Galia
Negro Francesco
Bibert Stephanie
Söderholm Jonas
Westin Johan
Lindh Magnus
Romero Ana
Missale Gabriele
Ferrari Carlo
Neumann Avidan U.
Pawlotsky Jean-Michel
Haagmans Bart L.
Zeuzem Stefan
Bochud Pierre-Yves
Hellstrand Kristoffer

February 2011

predict spontaneous resolution of HCV infection and outcome of treatment among HCV genotype 1 infec...

Cumulative rates of SVR based on the Kaplan-Meier method.

Nobuhiro Harada (3410)
Sumihito Tamura (530879)
Yasuhiko Sugawara (530880)
Junichi Togashi (530881)
Takeaki Ishizawa (530882)
Junichi Kaneko (530883)
Taku Aoki (530884)
Yoshihiro Sakamoto (530885)
Kiyoshi Hasegawa (530886)
Tomohiro Tanaka (513251)
Noriyo Yamashiki (465622)
Norihiro Kokudo (530887)

March 2014

A. Stratified by EVR, B. HCV genotype, C. major allele (TT) in the recipient, and D. major allele...

SVR and RVR rates according to INF-L3 and HCV genotype.

Steffen B. Wiegand (642890)
Benjamin Heidrich (345028)
Simone Susser (48294)
Magdalena Rogalska-Taranta (285584)
Jörg Petersen (76825)
Klaus H. W. Böker (642894)
Natalia Grigorian (839704)
Ralph Link (642892)
Uwe Naumann (642896)
Christine John (839705)
Stefan Lueth (839706)
Peter Malfertheiner (144819)
Michael P. Manns (92947)
Heiner Wedemeyer (32361)
Christoph Sarrazin (48298)
Markus Cornberg (32357)

January 2016

(A) SVR rates in relation to IFNL3 genotype (PP analysis). (B) RVR rates in relation to IF...

Univariate and multivariate analyses for identification of independent predictive factors for SVR in HCV-2a- and -2b-infected patients treated with PEG-IFN/RBV therapy.

Ahmed El-Shamy (185397)
Ikuo Shoji (127861)
Soo-Ryang Kim (185402)
Yoshihiro Ide (185406)
Susumu Imoto (185410)
Lin Deng (127858)
Seitetsu Yoon (185415)
Takashi Fujisawa (185418)
Satoshi Tani (185420)
Yoshihiko Yano (185421)
Yasushi Seo (185424)
Takeshi Azuma (153452)
Hak Hotta (127864)

February 2012

Abbreviations: SVR, sustained virological response; IRRDR[2a], interferon/ribavirin resistance-de...

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and baseline HCV viral load.

Barham K. Abu Dayyeh (342522)
Namrata Gupta (229166)
Kenneth E. Sherman (171505)
Paul I. W. de Bakker (61332)
Raymond T. Chung (214536)

February 2013

Area under ROC for predicting SVR from a model including IL28B genotype (rs12979860) and b...

On-treatment responses of the DITTO-HCV genotype 1 patients grouped below or above the sCD26 600 ng/mL cut-off concentration prior to start of therapy.

Jonas Söderholm (355580)
Jesper Waldenström (380139)
Galia Askarieh (321575)
Massimo Pilli (179843)
Pierre-Yves Bochud (205597)
Francesco Negro (205592)
Jean-Michel Pawlotsky (355584)
Stefan Zeuzem (22856)
Carlo Ferrari (179895)
Gunnar Norkrans (321586)
Rune Wejstål (380140)
Johan Westin (321583)
Avidan U. Neumann (255364)
Bart L. Haagmans (253561)
Magnus Lindh (315102)
Gabriele Missale (139494)
Kristoffer Hellstrand (321584)
Martin Lagging (321589)

February 2013

Median (range) or individuals (percent). Statistics using aMann-Whitney U test ...

Baseline demographic and immuno-virological characteristics of patients according SVR.

Giulia Marchetti (131632)
Paola Nasta (182198)
Francesca Bai (131622)
Francesca Gatti (182206)
Giusi Maria Bellistrì (182213)
Camilla Tincati (182218)
Federica Borghi (182223)
Giampiero Carosi (182226)
Massimo Puoti (182231)
Antonella d'Arminio Monforte (182235)

February 2012

LEGEND. Data are presented as *median, (IQR) and °absolute number, (%). Differences betwee...

Predictive values for SVR among the DITTO-HCV genotype 1 patients included in the study.

Abstract

Extracted data

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