Morphology characterization of apoA-I mutants’ aggregates.

<p>Analysis of images observed under AFM. ApoA-I Wt (A), Gly26Arg (B) and Lys107-0 (C) respectively, were incubated for 24 h at 0.6 mg/mL and loaded onto mica. Small size oligomers covering the surface of the mica were predominant in each sample. The distribution of the oligomers’ height is shown as Histograms obtained from the measurement in the z-plane of 100 oligomers. Insets in the histograms’ plot represent isolated aggregates occasionally observed by negative stain under Transmission Electron Microscopy. Bars in each image show the scale used in each case.