<p>Graphs show the results of testing single estrogenic chemicals in the ERLUX (left) or ESCREEN (right) assays. Each single chemical was tested in three or more independent experiments. Results are shown as the best fit regression model, for which details are provided <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043606#pone-0043606-t002" target="_blank">Tables 2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043606#pone-0043606-t003" target="_blank">3</a>. Middle graph shows the correlation between EC10 values obtained in the ERLUX (y-axis) and ESCREEN (x-axis) assays.</p
In vitro estrogen receptor transactivation assays (ERTAs) are increasingly used to measure the overa...
This study was conducted to characterize the estrogen receptor (ER)–binding affinities of 50 chemica...
<p>For each plot, chemicals are ordered on the x-axis based on their hit call probability. The y axi...
<p>All agents were tested in at least four independent experiments, run on up to three micro-titer p...
<p>EC<sub>10</sub>, EC<sub>25</sub>: concentration provoking 10% and 25% effect, respectively. Value...
<p>EC<sub>10</sub>, EC<sub>25</sub>: concentration producing 10% and 25% effect, respectively. Value...
<p>Each graph shows the effect of a mixture of 16 modulators (A) or one of 16 individual modulators ...
<p><b>Copyright information:</b></p><p>Taken from "An Assessment of the Model of Concentration Addit...
<p><b>Copyright information:</b></p><p>Taken from "An Assessment of the Model of Concentration Addit...
<p>The estrogen equivalent quantity (EEQ) was defined as the sum of the concentration for each indiv...
<p>Each graph shows the distribution of toxic units as predicted by CA at the EC10 level for mixture...
<p>Observed mixture effects (black circles), controls (gray circles) and regression curve (solid bla...
<p>EC10: concentration associated with 10% proliferation rate. Values in brackets denote the upper a...
Copyright @ 1999 The National Institute of Environmental Health Sciences (NIEHS)The aim of this stud...
Thousands of environmental chemicals are subject to regulatory review for their potential to be endo...
In vitro estrogen receptor transactivation assays (ERTAs) are increasingly used to measure the overa...
This study was conducted to characterize the estrogen receptor (ER)–binding affinities of 50 chemica...
<p>For each plot, chemicals are ordered on the x-axis based on their hit call probability. The y axi...
<p>All agents were tested in at least four independent experiments, run on up to three micro-titer p...
<p>EC<sub>10</sub>, EC<sub>25</sub>: concentration provoking 10% and 25% effect, respectively. Value...
<p>EC<sub>10</sub>, EC<sub>25</sub>: concentration producing 10% and 25% effect, respectively. Value...
<p>Each graph shows the effect of a mixture of 16 modulators (A) or one of 16 individual modulators ...
<p><b>Copyright information:</b></p><p>Taken from "An Assessment of the Model of Concentration Addit...
<p><b>Copyright information:</b></p><p>Taken from "An Assessment of the Model of Concentration Addit...
<p>The estrogen equivalent quantity (EEQ) was defined as the sum of the concentration for each indiv...
<p>Each graph shows the distribution of toxic units as predicted by CA at the EC10 level for mixture...
<p>Observed mixture effects (black circles), controls (gray circles) and regression curve (solid bla...
<p>EC10: concentration associated with 10% proliferation rate. Values in brackets denote the upper a...
Copyright @ 1999 The National Institute of Environmental Health Sciences (NIEHS)The aim of this stud...
Thousands of environmental chemicals are subject to regulatory review for their potential to be endo...
In vitro estrogen receptor transactivation assays (ERTAs) are increasingly used to measure the overa...
This study was conducted to characterize the estrogen receptor (ER)–binding affinities of 50 chemica...
<p>For each plot, chemicals are ordered on the x-axis based on their hit call probability. The y axi...