Effect of PEA on GFAP expression, a marker of the activation of astrocytes.

<p>Western blot analysis showed a significant expression of GFAP in SN. PEA treatment significantly reduced the activation of astrocytes after MPTP injection. The relative expression of the protein band (∼50 kDa) was standardized for densitometric analysis to β-actin levels, and reported in panel <b>a1</b> are expressed as mean ± s.e.m. from n = 5/6 brains for each group. ***<i>P</i><0.001 <i>versus</i> sham, ^###<i>P</i><0.001 <i>versus</i> MPTP+vehicle.