Histology from lungs harvested on day 30 following adoptive transfer of day 60 macrophages isolated at day 60 from MHC class II Ab administered mice.

<p>0.1, and 1×10⁵ CD11b+ macrophages intrabronchially, and single intrabronchial administration of MHC class II Ab was done for adoptive transfer experiments. (A, B) H&E staining of the lungs collected from day 30 without (A) and with (B) adoptive transfer of 1×10⁵ CD11b+ macrophages following single administration of MHC class II Ab. (C, D) Trichrome staining of the lungs collected from day 30 without (C) and with (D) adoptive transfer of 1×10⁵ CD11b+ macrophages following single administration of MHC class II Ab; and (E) serum concentration of Abs to self-Ags ColV and Kα1T analyzed by ELISA. The data is represented as a mean ± SEM over a 5 different animals in each group, the significance (<i>p</i>-value <0.05) was determined by student-t-test and represented with an asterisk (*).