Linear response and relation between synaptic weight and effective coupling strength .

<p><b>A</b>: Firing-rate deflection of a LIF neuron caused by an incoming spike event of postsynaptic amplitude . <b>B</b>: Integral of the firing rate deflection shown in A as a function of the postsynaptic amplitude (simulation: black dots; analytical approximation (45) : gray curve). The neuron receives constant synaptic background input with , , and rates , resulting in a first and second moment (42) and . Simulation results are obtained by averaging over trials of duration each with input impulses on average. For further parameters of the neuron model, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002596#pcbi-1002596-t001" target="_blank">Table 1</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002596#pcbi-1002596-t002" target="_blank">Table 2</a>.