(<b>A</b>) <b>Lipid peroxidation increases significantly in parallel to increased DNA damage in post pubescent males (p<0.0001).</b>

<p> The subjects were aged between 15–77 years (n = 19). Spearman's correlation coefficient, r = 0.7209. An exponential (first-order) least squares fit was used to generate the nonlinear trend line. (<b>B</b>) <b>PARP activity decreases in line with a decline in NAD⁺ levels in post pubescent male subjects (p = 0.0149). .</b> The subjects were aged between 15–77 years (n = 19). Pearson's correlation coefficient,r = −0.5491 An exponential (first-order) least squares fit was used to generate the nonlinear trend line. (<b>C</b>) <b>Correlation between NAD⁺ levels and SIRT1 activity in post pubescent male subjects.</b> The subjects were aged between 15–77 years (n = 19). The correlation is not of statistical significance (p = 0.9829). Pearson's correlation coefficient,r = −0.005263.