<p>Rows 2 to 7 show types of cells forming a model population and their kinetic parameters. Row 7 shows population <i>V</i><sub>max</sub> and <i>K</i><sub>M,</sub> obtained by averaging single-cell <i>V</i><sub>max</sub> and <i>K</i><sub>M</sub>. Row 8 shows population <i>V</i><sub>max</sub> and <i>K</i><sub>M,</sub> obtained by fitting population kinetics to the integrated Michaelis-Menten equation.</p
Kinetic models of metabolism can be constructed to predict cellular regulation and devise metabolic ...
The various conditions and parameter values for each cell type, where n indicates the number of cell...
The two‐phase (G and C phases) model first proposed by Burns & Tannock (1970) to describe the cell c...
<p>Determination of <i>V</i><sub>max</sub> and <i>K</i><sub>M</sub> for cell population by averaging...
<p>Simulation of single-cell and population kinetics of a Michaelis-Menten-type reaction. <b><i>A</i...
<p>These numbers were obtained by a simulation with the parameters set that gave the best fit to the...
<p>Parameter estimates for the models of target cell kinetics in blood and spleen.</p
This chapter introduces the kinetic models of metabolism followed by examples on the construction of...
<p>Estimates for baseline rates (unit yr<sup>−1</sup> per cell) of cell-kinetic processes in the two...
<p>*Initial rate at each substrate concentration was fitted into Michaelis-Menten equation to determ...
<p>Plots showing the results of <i>Linear Noise Approximation</i> (a) and <i>Stochastic simulation</...
We introduce a methodology based on the Luria–Delbrück fluctuation model for estimating the cell kin...
a b s t r a c t An increasing number of industrial bioprocesses capitalize on living cells by using ...
The paper is aimed at determining the marginal distributions of the estimates of model parameters fo...
<p>The individual steps of the computational workflow are described in detail in the <a href="http:/...
Kinetic models of metabolism can be constructed to predict cellular regulation and devise metabolic ...
The various conditions and parameter values for each cell type, where n indicates the number of cell...
The two‐phase (G and C phases) model first proposed by Burns & Tannock (1970) to describe the cell c...
<p>Determination of <i>V</i><sub>max</sub> and <i>K</i><sub>M</sub> for cell population by averaging...
<p>Simulation of single-cell and population kinetics of a Michaelis-Menten-type reaction. <b><i>A</i...
<p>These numbers were obtained by a simulation with the parameters set that gave the best fit to the...
<p>Parameter estimates for the models of target cell kinetics in blood and spleen.</p
This chapter introduces the kinetic models of metabolism followed by examples on the construction of...
<p>Estimates for baseline rates (unit yr<sup>−1</sup> per cell) of cell-kinetic processes in the two...
<p>*Initial rate at each substrate concentration was fitted into Michaelis-Menten equation to determ...
<p>Plots showing the results of <i>Linear Noise Approximation</i> (a) and <i>Stochastic simulation</...
We introduce a methodology based on the Luria–Delbrück fluctuation model for estimating the cell kin...
a b s t r a c t An increasing number of industrial bioprocesses capitalize on living cells by using ...
The paper is aimed at determining the marginal distributions of the estimates of model parameters fo...
<p>The individual steps of the computational workflow are described in detail in the <a href="http:/...
Kinetic models of metabolism can be constructed to predict cellular regulation and devise metabolic ...
The various conditions and parameter values for each cell type, where n indicates the number of cell...
The two‐phase (G and C phases) model first proposed by Burns & Tannock (1970) to describe the cell c...