Combination therapy.

<p>Mouse pancreatic tumor cells (panc2) were implanted subcutaneously and treated with two doses of gemcitabine, alone or in combination with halofuginone. A– Tumor volume during 30 days. B– Tumor weight at the end of the experiment. C– Effects of halofuginone and gemcitabine on the number of host cells in the tumor. D– Effects of halofuginone and gemcitabine on apoptosis of all cells within the tumor, or of the cells that expressed αSMA. Results are means ± SE and columns with different letters within each experiment differ significantly (<i>P</i><0.05).