Detection of Env-CN54 gp140 specific CD8+ T cells in the GALT of vaccinated mice.

<p>The frequencies of CD8+ T cells secreting cytokines in response to CN54 peptide pools were evaluated in the mesenteric lymph nodes (MLN) of vaccinated mice at week 11 (A) and at week 15 (B). Graphs show the median CD8+ T-cell responses from the MLN (white bars) and from spleen (black bars) following stimulation with peptide pool 1. C) Effector memory T-cell numbers within the MLN were determined as described for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042163#pone-0042163-g005" target="_blank">Figure 5</a>. Each data point corresponds to a single mouse in the experimental group.