<p>Xenografted tumors were fixed, embedded and sectioned. Immunohistochemical staining of tumors for PR, Ki67 and cleaved casapse-3 (CC3) was performed.</p
<p>(<b>A</b>) ICR-nude mice bearing the established A549 tumors (∼50 mm<sup>3</sup>) were treated wi...
<p>Scale bars = 500 μm, 100 μm, and 50 μm (40X, 200X, and 400X), respectively.</p
<p>Mice were treated with vehicle, ziv-aflibercept and/or REGN1035. Tumors were harvested, processed...
<p>A, C and E: xenograft tumors from H1299/pCR3.1 cells; B, D and F: xenograft tumors from H1299/PAP...
<p>(A) KYSE70 cells were treated with the indicated concentrations of CYT-Rx20, followed by evaluati...
<p>(A) RT-PCR analysis of α5(IV) knockdown efficiency in A549 cells. (B-D) Knockdown of α5(IV) in A5...
<p>(A) The histological changes in tumor grafts were assessed using HE staining. Comparing the PBS c...
<p>Histologic sections were obtained from the tumors of the mice in each treatment group from the tu...
<p>(A) Cell apoptosis was evaluated using the TUNEL assay. Apoptotic cells (green) were counted from...
<p>(<b>A</b> and <b>C</b>) Representative Ki-67-stained images from paraffin sections of xenograft t...
<p>(A) Tumor regression in a xenograft model. The tumor volume was decreased after treatment with ci...
<p>Paraffin embedded tumor tissues were used for morphological analysis with H&E staining (A), proli...
<p>Excised tumors were fixed in formalin, paraffin embedded and sectioned. (<b>A</b>) H & E staining...
<p>(A) Animal experimental protocol was shown. (B to D) Comparisons of the tumor volumes between Huh...
<p>Immunohistochemical (IHC) analysis of Ki67 proliferation marker in treated tumor sections. Tumor ...
<p>(<b>A</b>) ICR-nude mice bearing the established A549 tumors (∼50 mm<sup>3</sup>) were treated wi...
<p>Scale bars = 500 μm, 100 μm, and 50 μm (40X, 200X, and 400X), respectively.</p
<p>Mice were treated with vehicle, ziv-aflibercept and/or REGN1035. Tumors were harvested, processed...
<p>A, C and E: xenograft tumors from H1299/pCR3.1 cells; B, D and F: xenograft tumors from H1299/PAP...
<p>(A) KYSE70 cells were treated with the indicated concentrations of CYT-Rx20, followed by evaluati...
<p>(A) RT-PCR analysis of α5(IV) knockdown efficiency in A549 cells. (B-D) Knockdown of α5(IV) in A5...
<p>(A) The histological changes in tumor grafts were assessed using HE staining. Comparing the PBS c...
<p>Histologic sections were obtained from the tumors of the mice in each treatment group from the tu...
<p>(A) Cell apoptosis was evaluated using the TUNEL assay. Apoptotic cells (green) were counted from...
<p>(<b>A</b> and <b>C</b>) Representative Ki-67-stained images from paraffin sections of xenograft t...
<p>(A) Tumor regression in a xenograft model. The tumor volume was decreased after treatment with ci...
<p>Paraffin embedded tumor tissues were used for morphological analysis with H&E staining (A), proli...
<p>Excised tumors were fixed in formalin, paraffin embedded and sectioned. (<b>A</b>) H & E staining...
<p>(A) Animal experimental protocol was shown. (B to D) Comparisons of the tumor volumes between Huh...
<p>Immunohistochemical (IHC) analysis of Ki67 proliferation marker in treated tumor sections. Tumor ...
<p>(<b>A</b>) ICR-nude mice bearing the established A549 tumors (∼50 mm<sup>3</sup>) were treated wi...
<p>Scale bars = 500 μm, 100 μm, and 50 μm (40X, 200X, and 400X), respectively.</p
<p>Mice were treated with vehicle, ziv-aflibercept and/or REGN1035. Tumors were harvested, processed...