Changes in specific subsets of microglia in the injured brain.

<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells, 91% were microglia. B: Representative cytometry data for CD86⁺/CD11b⁺ M1-like microglia in the brain at the indicated days after CCI. C: Representative cytometry data for CD206⁺/CD11b⁺ M2-like microglia in the brain at the indicated days after CCI. D: Graph illustrating quantitative data for CD86⁺/CD11b⁺ cells in the brain after CCI. CD86⁺/CD11b⁺ cells were higher in number than in the intact brain at 28 dpi. E: Graph illustrating quantitative data for CD206⁺/CD11b⁺ cells in the brain after CCI. CD206⁺/CD11b⁺ cells were higher in number at 7 dpi than in the intact brain, and decreased thereafter until 28 dpi. <i>n</i> = 3–5 for each group. * <i>p</i><0.05 compared with no injury.